121365-32-0Relevant academic research and scientific papers
Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands
Osman, Noha A.,Mahmoud, Amr H.,Allar, Marco,Niess, Raimund,Abouzid, Khaled A.,Marzo, Vincenzo Di,Abadi, Ashraf H.
experimental part, p. 8463 - 8477 (2011/02/26)
In the present work, we report upon the design, synthesis and biological evaluation of new anandamide derivatives obtained by modifications of the fatty acyl chain and/or of the ethanolamide 'tail'. The compounds are of the general formula: 6-(substituted
Computer based design, synthesis and biological evaluation of novel indole derivatives as HCV NS3-4A serine protease inhibitors
Ismail, Nasser S.M.,El Dine, Riham Salah,Hattori, Masao,Takahashi, Kazunori,Ihara, Masataka
, p. 7877 - 7887 (2008/12/23)
A series of novel indoles were designed and their molecular modeling simulation study including fitting to a 3D pharmacophore model using CATALYST program and their docking into the NS3 active site was examined as HCV NS3 protease inhibitor. Several compo
