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Usage

Uses

Used in Pharmaceutical Industry:
(2,5-dibromophenyl)methaneamine serves as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the creation of molecules with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (2,5-dibromophenyl)methaneamine is utilized as an intermediate for synthesizing compounds that have applications in agriculture, such as pesticides and herbicides. Its reactivity and structural features make it a valuable precursor in the development of effective agrochemical products.
Used in Organic Compounds Synthesis:
(2,5-dibromophenyl)methaneamine is also used as an intermediate in the synthesis of a variety of organic compounds. Its versatility in chemical reactions enables the production of a wide range of organic molecules for different applications.
Used in Dyes and Pigments Production:
(2,5-dibromophenyl)methaneamine finds application in the production of dyes and pigments due to its chemical structure and reactivity. Its bromine atoms contribute to the color and stability of the dyes and pigments, making it a useful component in this industry.
Used in Industrial Processes:
Due to its structural properties and reactivity, (2,5-dibromophenyl)methaneamine has potential applications in various industrial processes. It can be employed in the development of new materials, chemical reactions, and other processes that require its specific characteristics.

Upstream product

• 57381-43-8 2,5-dibromobenzoic acid methyl ester 
• 170492-50-9 2,5-dibromobenzamide 
• 615-59-8 1,4-dibromo-2-methylbenzene 
• 136105-40-3 1,4-dibromo-2-(bromomethyl)benzene 

Downstream Products

• 1613451-75-4 tert-butyl N-[(2,5-dibromophenyl)methyl]carbamate 

Relevant academic research and scientific papers

Synthesis, characterization and targeted cell imaging applications of poly(p-phenylene)s with amino and poly(ethylene glycol) substituents

A novel approach for bioconjugation associated with a fluorescent conjugated polymer is demonstrated. For this purpose, a conjugated polymer, poly(p-phenylene) (PPP), with lateral substituents, namely primary amino groups and poly(ethylene glycol) (PEG) chains, as a potential building block for polymer bioconjugates was synthesized and characterized. The synthesis was achieved through Suzuki polycondensation reaction in the presence of Pd(PPh3)4 catalyst by using independently prepared PEG and amino functionalized dibromo benzenes in conjunction with benzene diboronic acid. For the evaluation of the bioactive PPP labeled with folic acid (FA) as a potential targeted cell imaging probe, HeLa and A549 cancer cells were used. Cytotoxicity assay showed that the polymer was not toxic to either of the cells. Additionally, the fluorescence images showed that, depending on the level of the FA receptors on the cell surfaces, the fluorescent intensity in HeLa cells was obviously higher than A549 cells when treated with FA conjugated PPP-NH2-g-PEG polymer. The resulting FA/PPP-NH2-g-PEG conjugate was successfully used as a bioconjugate for targeting and specifically imaging FA receptor positive HeLa human cervical cancer cells.

Synthesis and characterization of polyphenylenes with polypeptide and poly(ethylene glycol) side chains

We report a novel approach for fabrication of multifunctional conjugated polymers, namely poly(p-phenylene)s (PPPs) possessing polypeptide (poly-l-lysine, PLL) and hydrophilic poly(ethylene glycol) (PEG) side chains. The approach is comprised of the combination of Suzuki coupling and in situ N-carboxyanhydride (NCA) ring-opening polymerization (ROP) processes. First, polypeptide macromonomer was prepared by ROP of the corresponding NCA precursor using (2,5-dibromophenyl)methanamine as an initiator. Suzuki coupling reaction of the obtained polypeptide and PEG macromonomers both having dibromobenzene end functionality using 1,4-benzenediboronic acid as the coupling partner in the presence of palladium catalyst gave the desired polymer. A different sequence of the same procedure was also employed to yield polymer with essentially identical structure. In the reverse sequence mode, low molar mass monomer (2,5-dibromophenyl)methanamine, and PEG macromonomer were coupled with 1,4-benzenediboronic acid in a similar way followed by ROP of the L-Lysine NCA precursor through the primary amino groups of the resulting polyphenylene.

METAL ORGANIC FRAMEWORKS COMPRISING A PLURALITY OF SBUS WITH DIFFERENT METAL IONS AND/OR A PLURALITY OF ORGANIC LINKING LIGANDS WITH DIFFERENT FUNCTIONAL GROUPS.

The disclosure provides for metal organic frameworks (MOFs) which comprise a plurality of SBUs comprising different metals or metal ions and/or a plurality of organic linking moieties comprising different functional groups.

Metal-organic frameworks with precisely designed interior for carbon dioxide capture in the presence of water

The selective capture of carbon dioxide in the presence of water is an outstanding challenge. Here, we show that the interior of IRMOF-74-III can be covalently functionalized with primary amine (IRMOF-74-III-CH2NH 2) and used for the selective capture of CO2 in 65% relative humidity. This study encompasses the synthesis, structural characterization, gas adsorption, and CO2 capture properties of variously functionalized IRMOF-74-III compounds (IRMOF-74-III-CH3, -NH2, -CH2NHBoc, -CH2NMeBoc, -CH 2NH2, and -CH2NHMe). Cross-polarization magic angle spinning 13C NMR spectra showed that CO2 binds chemically to IRMOF-74-III-CH2NH2 and -CH2NHMe to make carbamic species. Carbon dioxide isotherms and breakthrough experiments show that IRMOF-74-III-CH2NH2 is especially efficient at taking up CO2 (3.2 mmol of CO2 per gram at 800 Torr) and, more significantly, removing CO2 from wet nitrogen gas streams with breakthrough time of 610 ± 10 s g-1 and full preservation of the IRMOF structure.