136105-40-3

Basic information

• Product Name: 2,5-DibroMobenzyl broMide
• Synonyms: 2,5-DibroMobenzyl broMide;1,4-dibromo-2-(bromomethyl)benzene;Benzene, 1,4-dibromo-2-(bromomethyl)-
• CAS NO: 136105-40-3
• Molecular Formula: C₇H₅Br₃
• Molecular Weight: 328.84
• Mol File: 136105-40-3.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 311.7±27.0 °C(Predicted)
• Appearance: /
• Density: 2.173±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2,5-DibroMobenzyl broMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DibroMobenzyl broMide(136105-40-3)
• EPA Substance Registry System: 2,5-DibroMobenzyl broMide(136105-40-3)

Safety Data

• Hazardous Substances Data: 136105-40-3(Hazardous Substances Data)

Usage

General Description

2,5-Dibromobenzyl bromide is a chemical compound with the molecular formula C14H13Br2NO. It is a derivative of benzyl bromide, and it is commonly used as a reagent in organic synthesis. 2,5-DibroMobenzyl broMide is known for its ability to react with various nucleophiles, forming new carbon-carbon and carbon-heteroatom bonds. It is commonly used in the preparation of pharmaceuticals, agrochemicals, and other organic compounds. 2,5-Dibromobenzyl bromide is a valuable tool in the field of organic chemistry and plays a crucial role in the development of new chemical compounds.

Upstream product

• 76008-76-9 2,5-dibromobenzoic acid ethyl ester 
• 147034-01-3 (2,5-dibromophenyl)methanol 
• 610-71-9 2,5-dibromobenzoic acid 
• 615-59-8 1,4-dibromo-2-methylbenzene 
• 13822-09-8 benzyl peroxide 

Downstream Products

• 891865-62-6 3-(2,5-dibromophenyl)-2-methylpropionic acid 
• 13141-26-9 5-bromo-2-phenylbenzo[b]furan 
• 28718-78-7 5-Brom-2-(4-bromphenyl)-1-benzofuran 
• 503300-08-1 5-bromo-2-(4'-methoxyphenyl)benzofuran 
• 1214331-41-5 (2,5-dibromophenyl)methaneamine 
• 32917-57-0 2,5-dibromostyrene 
• 1343273-37-9 [(2,5-dibromophenyl)methyl](methyl)amine 
• 1613451-76-5 tert-butyl N-[(2,5-dibromophenyl)methyl]-N-methylcarbamate 
• 1034917-75-3 sodium 2,5-dibromobenzylsulfonate 
• 875550-82-6 C₂₉H₂₅BrF₇NO₃ 
• 74533-21-4 2-(2,5-dibromophenyl)acetonitrile 
• 1350840-06-0 2-(2,5-dibromophenyl)-N-methoxyacetamide 
• 203314-28-7 2-(2,5-dibromophenyl)-acetic acid 

Relevant articles and documents

Synthesis and characterization of a mesogen-jacketed polyelectrolyte

In an attempt to construct a new kind of rodlike polyelectrolyte, poly[sodium 2,5-bis(4′-sulfophenyl)styrene] (PSBSS) was prepared from its precursor, poly[2,5-bis(4′-neopentylsulfophenyl)styrene] (PBNSS), which was polymerized by atom transfer radical polymerization. Small-angle X-ray scattering (SAXS) results demonstrate that PBNSS exhibits a hexagonal columnar phase and PSBSS exhibits a smectic A phase in bulk. The conformation of PSBSS in the aqueous solution is cylindrical, and the length and the diameter of the cylinder are ca. 25 nm and ca. 2.4 nm, respectively. The persistence length (lp) of the PSBSS chain in the aqueous solution is 11.50 ± 0.09 nm calculated by fitting the SAXS profile with the modified wormlike chain model. The conformation, the maximum length, and the lp of the chain are only weakly dependent on the concentration of the added salt. These results indicate that we have successfully obtained a new kind of polyelectrolyte with a highly rigid chain, a high charge density, and a narrow molecular weight distribution, which can serve as a new model macromolecule in studying rodlike polyelectrolytes.

tBuOK-Promoted Cyclization of Imines with Aryl Halides

A transition-metal-free indole synthesis using radical coupling of 2-halotoluenes and imines via the later-stage C-N bond construction was reported for the first time. It includes an aminyl radical generation by C-H cleaving addition of 2-halotoluenes to imines via the carbanion radical relay and an intramolecular coupling of aryl halides with aminyl radicals. One standard condition can be used for all halides including F, Cl, Br, and I. No extra oxidant or transition metal is required.

ALDOSTERONE SYNTHASE INHIBITORS

The present invention relates to compounds of the formulas (IA) and (IB) and pharmaceutically acceptable salts thereof, wherein A and R1 - R6, are as defined herein. The invention also relates to pharmaceutical compositions comprisin