1215007-35-4Relevant academic research and scientific papers
Direct Catalytic Asymmetric Aldol Reaction of α-Alkylamides
Liu, Zijian,Takeuchi, Toshifumi,Pluta, Roman,Arteaga Arteaga, Fernando,Kumagai, Naoya,Shibasaki, Masakatsu
supporting information, p. 710 - 713 (2017/02/10)
A catalytic asymmetric aldol reaction directly employing amides as latent enolates has remained elusive because of the resistance of amides to enolization. A direct aldol reaction of α-alkylamides without any electron-withdrawing group harnessed by specif
Enantioselective synthesis of anti - And syn -homopropargyl alcohols via chiral Br?nsted acid catalyzed asymmetric allenylboration reactions
Chen, Ming,Roush, William R.
, p. 10947 - 10952 (2012/08/27)
Chiral Br?nsted acid catalyzed asymmetric allenylboration reactions are described. Under optimized conditions, anti-homopropargyl alcohols 2 are obtained in high yields with excellent diastereo- and enantioselectivities from stereochemically matched aldeh
Asymmetric aldol reactions using chiral CF3-Oxazolidines (Fox) as chiral auxiliary
Tessier, Arnaud,Pytkowicz, Julien,Brigaud, Thierry
experimental part, p. 1140 - 1144 (2010/03/02)
The aldol reactions of amide enolates derived from a trifluoromethylated oxazolidine (Fox) chiral auxiliary occur in good yields with a moderate anti diastereoselectivity (Li and Na enolates) to a high syn diastereoselectivity (boron enolate). After remov
