1215035-95-2Relevant academic research and scientific papers
Organocatalyst Efficiency in the α-Aminoxylation and α-Hydrazination of Carbonyl Derivatives in Aqueous Media or in a Ball-Mill
Veverková, Eva,Modrocká, Viktória,?ebesta, Radovan
, p. 1191 - 1195 (2017)
Pyrrolidine-derived organocatalysts have been tested in two types of α-heterofunctionalization reactions in aqueous media or under solvent-free ball-milling conditions. The best results in terms of both activity and enantioselectivity were obtained with O
Asymmetric α-amination of aldehydes by a recyclable resin-supported peptide catalyst
Tanaka, Tatsuyoshi,Akagawa, Kengo,Mitsuda, Masaru,Kudo, Kazuaki
, p. 294 - 296 (2013)
The asymmetric a-amination of aldehydes was performed using a resin-supported peptide catalyst. A tri- or tetrapeptide with an N-terminal D-Pro-Aib sequence efficiently catalyzed the reaction in a highly enantioselective manner. The supported catalyst could be easily recovered by filtration and reused at least ten times.
Direct asymmetric α-amination of aldehydes with azodicarboxylates in ionic liquids catalyzed by imidazolium ion-tagged proline organocatalyst
Ding, Xiong,Jiang, Hong-Lai,Zhu, Cheng-Jian,Cheng, Yi-Xiang
experimental part, p. 6105 - 6107 (2011/01/04)
Direct asymmetric α-amination of unmodified aldehydes with azodicarboxylates in ionic liquids in the presence of imidazolium ion-tagged l-proline organocatalyst 1 gives excellent enantioselectivities (up to 98% ee) and high chemical yields. The system can
Remarkable reaction rate and excellent enantioselective direct α-amination of aldehydes with azodicarboxylates catalyzed by pyrrolidinylcamphor-derived organocatalysts
Liu, Pang-Min,Chang, Chihliang,Reddy, Raju Jannapu,Ting, Ying-Fang,Kuan, Hsuan-Hao,Chen, Kwunmin
supporting information; experimental part, p. 42 - 46 (2010/03/24)
Remarkable reaction rate and excellent enantioselective direct α-amination of unmodified aldehydes with various azodicarboxylates was catalyzed by pyrrolidinylcamphor organocatalyst 2a (5 mol-%) to provide the desired aminated products with excellent chemical yields and high to excellent levels of enantioselectivity (up to >99%ee) at 0 °C in CH 2Cl2.
