Advanced Synthesis and Catalysis p. 294 - 296 (2013)
Update date:2022-08-30
Topics:
Tanaka, Tatsuyoshi
Akagawa, Kengo
Mitsuda, Masaru
Kudo, Kazuaki
The asymmetric a-amination of aldehydes was performed using a resin-supported peptide catalyst. A tri- or tetrapeptide with an N-terminal D-Pro-Aib sequence efficiently catalyzed the reaction in a highly enantioselective manner. The supported catalyst could be easily recovered by filtration and reused at least ten times.
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(2013)
