1215071-17-2

Basic information

• Product Name: tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
• Synonyms: 1-Piperidinecarboxylic acid, 3,3-difluoro-4-oxo-, 1,1-diMethylethyl ester;tert-Butyl 3,3-difluoro-4-oxopiperidin-1-carboxylate hydrate;tert-Butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate hydrate;tert-Butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate;1-(tert-Butyloxycarbonyl)-3,3-difluoro-4-oxopiperidine;3,3-Difluoro-4-oxo-piperidine-1-carboxylic acid tert-butyl ester;N-t-BOC-5,5-Difluoro-4-Piperidinone;EOS-61163
• CAS NO: 1215071-17-2
• Molecular Formula: C₁₀H₁₅F₂NO₃
• Molecular Weight: 235.2278064
• Mol File: 1215071-17-2.mol

Chemical Properties

• Boiling Point: 274.7±40.0 °C(Predicted)
• Appearance: /
• Density: 1.21±0.1 g/cm3(Predicted)
• PKA: -5?+-.0.40(Predicted)
• CAS DataBase Reference: tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate(1215071-17-2)
• EPA Substance Registry System: tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate(1215071-17-2)

Safety Data

• Hazardous Substances Data: 1215071-17-2(Hazardous Substances Data)

Usage

Uses

Used in Research Applications:
Tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate is used as a research chemical for [application reason], such as studying its chemical properties, potential reactions, or interactions with other compounds. Its unique structure makes it a valuable tool for scientists in the field of organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate is used as an intermediate or building block for the synthesis of more complex molecules, which could potentially lead to the development of new drugs or therapeutic agents. Its specific structure may offer unique properties that can be exploited in the design of novel pharmaceutical compounds.
Used in Chemical Synthesis:
Tert-butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate is used as a synthetic building block in the preparation of various organic compounds. Its unique structure allows for the creation of a wide range of molecules with different properties and potential applications, making it a valuable resource in the field of chemical synthesis.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1039741-54-2 1-benzyl-3,3-difluoropiperidin-4-one 
• 51779-32-9 iminodicarboxylic acid di-tert-butyl ester 
• 1523618-12-3 3,3-difluoropiperidin-4-one hydrochloride 
• 1423027-29-5 1-(4-methoxybenzyl)-3,3-difluoropiperidin-4-one 
• 1423027-26-2 ethyl 5,5-difluoro-1-(4-methoxybenzyl)-4-oxopiperidine-3-carboxylate 
• 1423027-23-9 ethyl 3-[(3-ethoxy-3-oxopropyl)(4-methoxybenzyl)amino]-2,2-difluoropropanoate 
• 1239596-54-3 3,3-difluoropiperidin-4-ol 
• 1239596-53-2 N-benzyl-3,3-difluoro-4-hydroxypiperidine 
• 1209780-71-1 tert-butyl 3,3-difluoro-4-hydroxy-piperidine-1-carboxylate 
• 1067914-81-1 3,3-difluoro-1-(phenylmethyl)-4,4-piperidinediol 

Downstream Products

• 1334412-95-1 tert-butyl 4-(2-ethoxy-2-oxoethyl)-3,3-difluoropiperidine-1-carboxylate 
• 1429256-79-0 C₁₆H₁₉BrF₂N₂O₂ 
• 1429256-80-3 C₁₇H₂₁BrF₂N₂O₂ 
• 1429256-81-4 C₁₇H₂₁BrF₂N₂O₂ 
• 1429256-82-5 C₁₇H₂₁BrF₂N₂O₂ 
• 1429256-83-6 C₁₉H₂₅BrF₂N₂O₂ 
• 1039741-54-2 1-benzyl-3,3-difluoropiperidin-4-one 
• 1373503-54-8 (±)-2-(1-( tert-butoxycarbonyl)-3,3-difluoropiperidin-4-yl)acetic acid 

Relevant articles and documents

COMPOUNDS USEFUL AS KINASE INHIBITORS

This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK).The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of Bruton's tyrosine kinase, for example cancer, lymphoma, leukemia and immunological diseases.

Novel synthesis of 4,4-difluoropyrido[4,3-b]indoles via intramolecular Heck reaction

Various difluoropyridoindoles were synthesized via a palladium-catalyzed intramolecular Heck reaction as a key step. Thus, ortho-bromoanilines and difluoropiperidinone were treated with (PPh3)2PdCl 2 and base in pyridine to give the regioselective cyclized heterocycles in modest to satisfactory yields. Copyright

Bridged Spiro[2.4]heptane Ester Derivatives

The invention relates to a method for preparing linear polymers having an amide end or having a star architecture comprising an amide core, by means of a ring opening using lactide and glycolide monomers or a lactide monomer ring in the presence of a cata

FLUORINATED BRIDGED SPIRO[2.4]HEPTANE DERIVATIVES AS ALX RECEPTOR AGONISTS

The present invention relates to fluorinated bridged spiro[2.4]heptane derivatives of formula (I), wherein n and R1 are as defined in the description, their preparation and their pharmaceutically active compounds.

BRIDGED SPIRO[2.4]HEPTANE ESTER DERIVATIVES

The present invention relates to bridged spiro[2.4]heptane ester derivatives of formula (I) wherein W, Y, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds.