121508-78-9

Basic information

• Product Name: N-[(E)-phenylmethylidene]-N-prop-2-ynylamine
• Synonyms: N-[(E)-phenylmethylidene]-N-prop-2-ynylamine
• CAS NO: 121508-78-9
• Molecular Weight: 143.188
• Mol File: 121508-78-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: N-[(E)-phenylmethylidene]-N-prop-2-ynylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(E)-phenylmethylidene]-N-prop-2-ynylamine(121508-78-9)
• EPA Substance Registry System: N-[(E)-phenylmethylidene]-N-prop-2-ynylamine(121508-78-9)

Safety Data

• Hazardous Substances Data: 121508-78-9(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 151231-68-4 N-(prop-2-ynyl)triphenyliminophosphorane 
• 2450-71-7 Propargylamine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 183963-69-1 diethyl phenyl(prop-2-yn-1-ylamino)methanephosphonate 
• 34014-16-9 4-Aminotetrolic acid 
• 57735-01-0 (1-Methyl-3-trimethylsilanyl-prop-2-ynyl)-[1-phenyl-meth-(E)-ylidene]-amine 
• 57790-33-7 [1-Phenyl-meth-(E)-ylidene]-(1-trimethylsilanylethynyl-but-3-ynyl)-amine 
• 57735-02-1 [1-Phenyl-meth-(E)-ylidene]-(1-trimethylsilanylethynyl-pentyl)-amine 
• 57735-00-9 methyl 4-(benzylideneamino)-6-(trimethylsilyl)-5-hexynoate 
• 5221-67-0 5-methyl-2-phenyloxazole 
• 111493-11-9 (E)-3-benzyl-5-(iodomethylene)-1,3-oxazolidin-2-one 
• 1041425-04-0 N-benzyl-N-(2-propynyl)-2-chloroacetamide 
• 1007389-70-9 3-benzyl-6-methyl-3,4-dihydro-2H-1,3-oxazin-2-one 

Relevant articles and documents

Reductive Amination Revisited: Reduction of Aldimines with Trichlorosilane Catalyzed by Dimethylformamide─Functional Group Tolerance, Scope, and Limitations

Aldimines, generated in situ from aliphatic, aromatic, and heteroaromatic aldehydes and aliphatic, aromatic, and heteroaromatic primary or secondary amines, can be reduced with trichlorosilane in the presence of dimethylformamide (DMF) as an organocatalys

Iodocarbamation of N-Homopropargyl Carbamates: Mild and Stereoselective Entry to Functionalized Oxazinan-2-ones

An efficient and general iodocarbamation of benzyl N-homopropargylcarbamates has been developed by using iodine as the electrophilic agent. This regio- and stereoselective cyclization yielded (E)-6-iodomethyleneoxazinan-2-ones, which can be further transformed through palladium cross-coupling reactions followed by hydrogenation to produce 1,3-oxazinan-2-ones.

An expeditious and atom-economic synthesis of lead-like, medicinally important 4,5-dihydropyrazolo[1,5-a]pyrazin-6-ones

We have developed an expeditious and atom-economic synthesis of lead-like, privileged 4,5-dihydropyrazolo[1,5-a]pyrazin-6-ones, which is based on Sonogashira coupling and a two-step condensation with hydrazine hydrate leading to two ring-forming events, with full control over the two elements of diversity present.