121513-89-1

Basic information

• Product Name: 4-(4-methoxyphenyl)-2-(p-tolyl)quinazoline
• Synonyms: 4-(4-methoxyphenyl)-2-(p-tolyl)quinazoline
• CAS NO: 121513-89-1
• Molecular Weight: 326.398
• Mol File: 121513-89-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(4-methoxyphenyl)-2-(p-tolyl)quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methoxyphenyl)-2-(p-tolyl)quinazoline(121513-89-1)
• EPA Substance Registry System: 4-(4-methoxyphenyl)-2-(p-tolyl)quinazoline(121513-89-1)

Safety Data

• Hazardous Substances Data: 121513-89-1(Hazardous Substances Data)

Upstream product

• 18818-41-2 2-(4-methylphenyl)-4(3H)-quinazolinone 
• 5720-07-0 4-methoxyphenylboronic acid 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Relevant articles and documents

Nickel-catalyzed Kumada Cross-coupling Reaction for the Synthesis of 2,4-Diarylquinazolines

A series of 2,4-diarylquinazolines have been successfully synthesized via the Ni-catalyzed cross-coupling reaction of quinazoline-4-tosylates and aryl Grignard reagents, which provided alternative straightforward approaches for the introduction of aryl groups to quinazolines at C-4 position.

Synthesis of 4-arylquinazolines by arylation of quinazolin-4-ones under mild conditions

An efficient route to 4-arylquinazolines via arylation of quinazolin-4-ones under mild condition is described. The reaction is carried out by the palladium-catalyzed coupling of quinazolin-4-ones with arylboronic acids in the presence of TsCl leading to 4-arylquinazolines in good to excellent yields. Georg Thieme Verlag Stuttgart New York.