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ethyl 2-(4-methylphenylimino)acetate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

121641-60-9

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121641-60-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 121641-60-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,6,4 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 121641-60:
(8*1)+(7*2)+(6*1)+(5*6)+(4*4)+(3*1)+(2*6)+(1*0)=89
89 % 10 = 9
So 121641-60-9 is a valid CAS Registry Number.

121641-60-9Relevant articles and documents

Visible-Light-Induced Dehydrogenative Imidoylation of Imidazo[1,2- a]pyridines with α-Amino Acid Derivatives and α-Amino Ketones

Zhu, Zhi-Qiang,Guo, Dong,Ji, Jiu-Jian,Zhu, Xiao,Tang, Juan,Xie, Zong-Bo,Le, Zhang-Gao

, p. 15062 - 15071 (2020)

A new and efficient visible-light-promoted dehydrogenative cross-coupling reaction of imidazo[1,2-a]pyridines with α-amino carbonyl compounds toward imidoyl imidazo[1,2-a]pyridines is developed. A diverse range of imidazo[1,2-a]pyridines undergoes the dehydrogenative imidoylation smoothly with α-amino carbonyl compounds to access the corresponding products in satisfactory yields. We have also proposed the possible reaction mechanism based on preliminary mechanistic studies. The synthetic method has the advantages of wide substrate scope, good functional tolerance, and mild reaction conditions, which make this transformation more practical and sustainable.

A Catalytic Approach to Quinoline Fused Lactones and Lactams from Glycine Derivatives

Huo, Congde,Yuan, Yong,Chen, Fengjuan,Wang, Yajun

, p. 3648 - 3654 (2015)

A dual catalyst system [copper(II) chloride-sulfuric acid, (CuCl2-H2SO4)]-promoted aerobic oxidative reaction of glycine derivatives with 2,3-dihydrofurans or 2,3-dihydropyrroles has been explored, affording an efficient synthesis of high value quinoline fused lactones and lactams. The application of this new methodology to the synthesis of a bioactive C ring extension analogue of luotonin A has been accomplished in a concise three-step sequence.

Copper-Catalyzed Aerobic Oxidative Dehydrogenative Formal [2 + 3] Cyclization of Glycine Esters with α-Angelicalactone: Approach To Construct Polysubstituted Pyrrolidones

Huo, Congde,Yuan, Yong,Chen, Fengjuan,Tang, Jing,Wang, Yajun

, p. 4208 - 4211 (2015)

A novel and efficient copper-catalyzed aerobic oxidative dehydrogenative formal [2 + 3] cyclization of glycine derivatives with α-angelicalactone is described. A series of complex pyrrolidones were produced under mild and simple reaction conditions.

Enol ethers as carbonyl surrogates in a modification of the Povarov synthesis of 3-aryl quinolines and their anti-Toxoplasma activity

Brown, Carla E.,McNulty, James,Bordón, Claudia,Yolken, Robert,Jones-Brando, Lorraine

, p. 5951 - 5955 (2016)

A novel method for the preparation of 2-carboxyl-3-aryl quinoline derivatives from anilines, ethyl glyoxalate and enol ethers as phenylacetaldehyde surrogates is reported. The three-component coupling reaction occurs rapidly under mild conditions in dichl

Photoinduced iodine-mediated tandem dehydrogenative Povarov cyclisation/C-H oxygenation reactions

Brasholz, Malte,Schendera, Eva,Villinger, Alexander

, p. 6912 - 6915 (2020)

We report metal-free, photoinduced aerobic tandem dehydrogenative Povarov cyclisation/Csp3-H oxygenation reactions between N-aryl glycine esters and α-substituted styrenes, which efficiently lead to 4,4-disubstituted dihydroquinoline-3-ones under mild conditions. The reactions are mediated by iodine along with visible light irradiation, which allows for the in situ generation of the essential Br?nsted acid HI, to catalyse the key imine [4+2]-cycloaddition.

Cobalt-Catalyzed Oxidative Phosphonylation of α-Amino Acid Derivatives and α-Amino Ketones for α-Aminophosphonates

Zhu, Zhi-Qiang,Xiao, Li-Jin,Guo, Dong,Chen, Xu,Ji, Jiu-Jian,Zhu, Xiao,Xie, Zong-Bo,Le, Zhang-Gao

, p. 435 - 442 (2019)

A novel and efficient direct oxidative phosphonylation of α-amino ketones and α-amino acid derivatives with dialkyl phosphites by the catalysis of a cobalt salt under air is disclosed. A variety of α-amino ketones and α-amino acid derivatives underwent th

Br?nsted Acid-Catalyzed Three-Component Reaction of Anilines, α-Oxoaldehydes, and α-Angelicalactone for the Synthesis of Complex Pyrrolidones

Huo, Congde,Yuan, Yong

, p. 12704 - 12710 (2015)

A green and efficient three-component reaction of easily available anilines, α-oxoaldehydes, and α-angelicalactone was developed for the synthesis of highly functionalized pyrrolidones using dilute sulfuric acid as the catalyst. Products were obtained in good to high yields at room temperature and under solvent-free conditions. The reaction could also be performed on a multigram scale with the same efficiency.

Tin powder-promoted oxidation/allylation of glycine esters: Synthesis of γ,δ-unsaturated α-amino acid esters

Zhao, Pengfei,Huang, Danfeng,Wang, Feng,Han, Tongyu,Yang, Ming,Wang, Ke-Hu,Hu, Yulai

, (2021/10/20)

An efficient tin powder-promoted oxidation/allylation reaction of glycine esters with allyl bromides is developed, which affords γ,δ-unsaturated α-amino acid esters under mild conditions without any other transition metal catalysts. This method avoids the use of unstable imine as starting material, and provides an efficient method for synthesis of γ,δ-unsaturated α-amino acid esters and α-methylene-γ-lactam derivatives. Additional supporting information may be found in the online version of this article at the publisher's web site.

Visible-Light-Mediated, Chemo- and Stereoselective Radical Process for the Synthesis of C-Glycoamino Acids

Ji, Peng,Zhang, Yueteng,Wei, Yongyi,Huang, He,Hu, Wenbo,Mariano, Patrick A.,Wang, Wei

supporting information, p. 3086 - 3092 (2019/05/01)

An approach for efficient synthesis of C-glycosyl amino acids is described. Different from typical photoredox-catalyzed reactions of imines, the new process follows a pathway in which α-imino esters serve as electrophiles in chemoselective addition reactions with nucleophilic glycosyl radicals. The process is highlighted by the mild nature of the reaction conditions, the highly stereoselectivity attending C-C bond formation, and its applicability to C-glycosylations using both armed and disarmed pentose and hexose derivatives.

Polarity-Reversed Addition of Enol Ethers to Imines under Visible Light: Redox-Neutral Access to Azide-Containing Amino Acids

Yang, Sen,Zhu, Shuangyu,Lu, Dengfu,Gong, Yuefa

supporting information, p. 8464 - 8468 (2019/10/14)

A three-component and polarity-reversed addition cascade with a glyoxylate-based imine, an enol ether, and TMSN3 was established for the construction of γ-azido amino acids under visible light. This transformation features mild and redox-neutra

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