121668-38-0

Basic information

• Product Name: (4S,5S)-2,2-diMethyl-1,3-Dioxolane-4,5-dicarboxylic acid 4,5-bis(1-Methylethyl) ester
• Synonyms: (4S,5S)-2,2-diMethyl-1,3-Dioxolane-4,5-dicarboxylic acid 4,5-bis(1-Methylethyl) ester;(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylic Acid 4,5-Bis(isopropyl) Ester,99%e.e.;(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylic Acid 4,5-Bis(isopropyl) Ester
• CAS NO: 121668-38-0
• Molecular Formula: C13H22O6
• Molecular Weight: 274.31018
• Mol File: 121668-38-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4S,5S)-2,2-diMethyl-1,3-Dioxolane-4,5-dicarboxylic acid 4,5-bis(1-Methylethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-2,2-diMethyl-1,3-Dioxolane-4,5-dicarboxylic acid 4,5-bis(1-Methylethyl) ester(121668-38-0)
• EPA Substance Registry System: (4S,5S)-2,2-diMethyl-1,3-Dioxolane-4,5-dicarboxylic acid 4,5-bis(1-Methylethyl) ester(121668-38-0)

Safety Data

• Hazardous Substances Data: 121668-38-0(Hazardous Substances Data)

Usage

General Description

The chemical compound "(4S,5S)-2,2-diMethyl-1,3-Dioxolane-4,5-dicarboxylic acid 4,5-bis(1-Methylethyl) ester" is an ester derivative of a dioxolane dicarboxylic acid. It has a molecular structure containing two methyl groups and two carboxylic acid groups, with two isopropyl groups attached to the ester functional group. (4S,5S)-2,2-diMethyl-1,3-Dioxolane-4,5-dicarboxylic acid 4,5-bis(1-Methylethyl) ester is commonly used in organic synthesis and pharmaceutical research due to its unique structure and potential applications in drug development. It may also have industrial uses as a chemical intermediate or a building block in the production of other compounds. Due to its specific stereochemistry and functional groups, this compound may have valuable properties that are of interest to researchers in various scientific fields.

Upstream product

• 2217-15-4 L-(+)-diisopropyl tartrate 
• 77-76-9 2,2-dimethoxy-propane 
• 37031-29-1 (+)-dimethyl-2,3-O-isopropylidene-D-tartrate 
• 67-63-0 isopropyl alcohol 
• 116499-08-2 dimethyl 2,2-dimethyl-1,3-dioxolane-trans-4,5-dicarboxylate 
• 62961-64-2 D-(-)-diisopropyl tartrate 
• 37031-29-1 (-)-dimethy-2,3-O-isopropylidene-L-tartrate 

Downstream Products

• 73346-74-4 (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol 
• 78469-77-9 1-O-benzyl-2,3-O-isopropylidene-D-threitol 
• 91548-58-2 ethyl (2E)-3-{(4R,5R)-5-[(benzyloxy)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl}acrylate 
• 1616868-90-6 C₁₈H₂₆O₅ 
• 1616868-91-7 C₁₆H₂₄O₄ 
• 1616868-92-8 (E)-ethyl 5-((4R,5R)-5-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)pent-2-enoate 
• 1616868-93-9 C₁₈H₂₆O₄ 
• 1616868-94-0 ((2S,3S)-3-(2-((4R,5R)-5-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)ethyl) oxiran-2-yl)methanol 
• 1374433-25-6 (4R,5S)-4-(benzyloxymethyl)-5-(chloromethyl)-2,2-dimethyl-1,3-di-oxolane 
• 338385-70-9 (4S,5S)-5-[(R)-(tert-Butyl-dimethyl-silanyloxy)-phenyl-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 214678-52-1 {(4R,5S)-5-[(R)-{[(tert-butyl)(dimethyl)silyl]oxy}(phenyl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl}methanol 

Relevant articles and documents

Stereoselective total synthesis of crassalactone A, a natural cytotoxic styryl lactone

A stereoselective total synthesis of a naturally occurring cytotoxic styryl lactone, crassalactone A (1), has been accomplished. The synthesis involves (-)-diisopropyl D-tartrate as the starting material, and the stereoselective additions of Grignard reag

The effects of different ester and ketal protecting groups on the reactivity and selectivity of tartrate-derived silylketene acetals

The reaction of tartrate-derived silylketene acetals and benzaldehyde has been investigated and the yields and diastereoselectivities have been found to be dependent upon the nature of the tartrate ester. Utilising the di-to7-butyl tartrate derivatives, high yields were achieved using a variety of aldehyde substrates. The reactions all proceeded with excellent levels of stereoselectivity (== 82:18); the sense of induction being dependent upon the choice of Lewis acid. BF3-OEt2 and TiCl3(OiPr) furnished complementary products in several cases and a model has been proposed to account for this observation.

Conformational Diagnosis of Diethyl (4S,5S)-4,5-Bis(tert-butyldimethylsiloxy)-2E,6E-octadienedioate Based on the Stereochemical Outcomes of Representative Reactions As Compared with Those of Its 4,5-O-Isopropylidene Derivatives and on a Dichroic Exciton C

In order to gain more insight into the conformation of diethyl (4S,5S)-4,5-bis(tert-butyldimethylsiloxy)-2E,6E-octadienedioate (1) experimentally, some appropriate reactions of 1 and its derivative (S,S)-3, which bears isopropylidene protecting groups, ha