338385-70-9

Upstream product

• 81801-09-4 4-O-benzyl-2,3-O-isopropylidene-D-threose 
• 20698-91-3 (R)-methyl mandelate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 130115-07-0 (R)-2-(t-butyldimethylsilyloxy)-2-phenylacetaldehyde 
• 145554-06-9 [(4R,5R)-5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 
• 73346-74-4 (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol 
• 121668-38-0 bis(1-methylethyl) (4S,5S)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate 
• 125993-65-9 (4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde 
• 124876-74-0 Methyl (R)-(-)-α-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-α-phenylacetate 
• 179618-33-8 ethyl (2E,4S)-4-{[(tert-butyl)(dimethyl)silyl]oxy}-4-phenylbut-2-enoate 
• 179618-34-9 ethyl (2S,3S,4R)-4-{[(tert-butyl)(dimethyl)silyl]oxy}-2,3-dihydroxy-4-phenylbutanoate 
• 187931-99-3 ethyl (4S,5S)-5-[(R)-{[(tert-butyl)(dimethyl)silyl]oxy}(phenyl)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 338385-68-5 (4S)-4-t-butyldimethylsilyloxy-4-phenyl-2S,3S-O-isopropylidene-butyl benzyl ether 
• 338385-66-3 (4S)-4-hydroxy-4-phenyl-2S,3S-O-isopropylidene-butyl benzyl ether 

Downstream Products

• 338385-72-1 ethyl 7S-t-butyldimethylsilyloxy-7-phenyl-5S,6S-O-isopropylidene-4S-hydroxy-heptyn-2-oate 
• 246035-59-6 (4S,6R)-6-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-4-hydroxy-tetrahydro-2H-2-pyranone 
• 1256338-97-2 2-{(4R,5S)-5-[(R)-{[(tert-butyl)(dimethyl)silyl]oxy}(phenyl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl}ethanol 
• 918907-25-2 (2S,3S)-2-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-6-oxo-3,6-dihydro-2H-pyran-3-yl (2E)-3-phenylprop-2-enoate 
• 338385-75-4 ethyl 7S-t-butyldimethylsilyloxy-7-phenyl-5S,6S-O-isopropylidene-4S-methoxymethyl-heptyn-2-oate 
• 338385-77-6 ethyl 7S-t-butyldimethylsilyloxy-7-phenyl-5S,6S-O-isopropylidene-4S-methoxymethyl-hepten-2Z-oate 

Relevant academic research and scientific papers

Stereoselective total synthesis of crassalactone A, a natural cytotoxic styryl lactone

A stereoselective total synthesis of a naturally occurring cytotoxic styryl lactone, crassalactone A (1), has been accomplished. The synthesis involves (-)-diisopropyl D-tartrate as the starting material, and the stereoselective additions of Grignard reag

Concise stereoselective total synthesis of leiocarpin C

A simple and highly concise strategy has been developed for the stereoselective total synthesis of leiocarpin C starting from commercially available mandelic ester. The strategy utilizes the OsO4-catalyzed cis-hydroxylation and selective reduction with K-Selectride as key steps. Copyright

First total synthesis of (+)-crassalactone A

A simple and highly efficient first total synthesis of cytotoxic (+)-crassalactone A starting from (R)-mandelic acid is described. The strategy involves the osmium tetroxide-catalyzed cis-hydroxylation and the stereoselective addition of ethyl lithiopropi

Total synthesis of four diastereoisomers of Goniofufurone from D-(-)- or L-(+)-tartaric acid

(+) and (-)-Goniofufurones, (+) and (-)-8-epi-goniofufurones have been synthesized from D-(-) and L-(+)-tartaric acids by the addition of ethyl lithiopropiolate to a chiral aldehyde intermediate as a key step, in which LDA is the best base compared to n-BuLi plus Lewis acid YCl3 (cat.).