121732-71-6Relevant articles and documents
Solid phase synthesis of chiral 3-substituted quinazoline-2,4-diones
Gouilleux, Laurent,Fehrentz, Jean-Alain,Winternitz,Martinez, Jean
, p. 7031 - 7034 (2007/10/03)
The synthesis of chiral 3-substituted quinazoline-2,4-diones was performed starting from N-urethane anthranilamides. This synthetic pathway was applied in solid phase, from commercially available anthranilic acid that was bound to hydroxymethyl polystyrene resin via a carbamate linker. In both cases, cyclisation occurred under basic conditions to afford non-racemized quinazolinediones in high purity.
New synthesis of 1,4 benzodiazepine-2,5-diones by means of HCl gas catalyst
Akssira,Boumzebra,Kasmi,Dahdouh,Roumestant,Viallefont
, p. 2265 - 2272 (2007/10/02)
A new synthesis of 1,4-benzodiazepinediones 4, particularly 1,4-dihydro1H-1,4-benzodiazepine-2,5-dione, 4c key intermediate of metabolites cyclopenin 9, cyclopenol 10, cyclopeptine 11 and dehydrocyclopeptide 12, was achieved by action of dry HCl gas in DM