121802-88-8

Upstream product

• 30779-90-9 (E)-3-benzylidenechroman-4-one 
• 79-19-6 thiosemicarbazide 
• 24513-65-3 3-benzylidene-chroman-4-one 
• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Discovery of 3,3a,4,5-tetrahydro-2H-benzo[g]indazole containing quinoxaline derivatives as novel EGFR/HER-2 dual inhibitors

In the present study, twenty-five pyrazole-quinoxaline derivatives (4a-4y) were designed and synthesized, and their biological activity as potential EGFR or HER-2 kinase inhibitors was evaluated. Among them, compound 4l displayed better antiproliferative

Fused Heterocycles. Part 3. Synthesis and Stereochemistry of Benzopyrano- and Benzothiapyrano-Pyrazoles

Several tricyclic benzopyranopyrazole derivatives have been studied by 1H and 13C n.m.r. spectroscopy.They were prepared by treating 3-benzylidene-chromanones and -1-thiochromanones with semicarbazide or thiosemicarbazide: reactions which give only the cis-3-H,3a-H stereoisomers.