24513-65-3

Upstream product

• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 100-52-7 benzaldehyde 
• 30779-90-9 (E)-3-benzylidenechroman-4-one 
• 108-95-2 phenol 
• 6180-61-6 3-phenoxypropanol 
• 7170-38-9 3-phenoxypropanoic acid 

Downstream Products

• 417710-59-9 3-benzylchroman-4-ol 
• 78140-81-5 trans-3-benzylchroman-4-ol acetate 
• 137985-53-6 1-Phenyl-1H,10H-9-oxa-2-thia-4-aza-phenanthren-3-ylamine 
• 137985-61-6 11-hydroxy-4-phenyl-3,4,4a,5,11-pentahydro<1>benzopyrano<3,4-d>pyrimidine-2(1H)-thione 
• 87604-67-9 trans-7-phenyl-6H-6a,7-dihydro[1]benzopyrano[3,4-c]-[1,5]-benzothiazepine 
• 60206-81-7 (+/-)-(3R,4S)-3-benzylchroman-4-ol 
• 50684-40-7 3-benzyl-4-chromanone 
• 78140-81-5 cis-3-benzylchroman-4-ol acetate 
• 1314880-73-3 4-phenyl-2-(pyridin-2-yl)-5H-chromeno[4,3-b]pyridine 
• 65023-65-6 1,3-diphenyl-10H-9-oxa-4-azaphenanthrene 
• 1314880-90-4 4-phenyl-2-(thiophen-2-yl)-5H-chromeno[4,3-b]pyridine 
• 1314880-82-4 2-(furan-2-yl)-4-phenyl-5H-chromeno[4,3-b]pyridine 
• 14261-95-1 3'-phenylspiro[chroman-3,2'-oxiran]-4-one 
• 1392504-42-5 3'-phenylspiro[chroman-3,2'-oxiran]-4-one 

Relevant academic research and scientific papers

Synthesis, structure, and estrogenic activity of 2- and 3-substituted 2,3-dihydro-4H-1-benzopyran-4-ones

Molecules with potent estrogenic activity are ~270 A3 hydrophobic structures that encompass two hydroxyls among which is at least one phenol. However, compounds with only one phenol or devoid of such a ring have been shown to enhance ERα-mediat

BF3·OEt2-Mediated Tandem Annulation: A Strategy to Construct Functionalized Chromeno- and Pyrano-Fused Pyridines

A simple and efficient one-pot annulation of arylidenones, alkynes, and nitriles in the presence of BF3·OEt2 is described. A highly functionalized variety of N-substituted pyridine-fused chromeno and pyrano derivatives were obtained

A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases

A series of novel terpyridine-skeleton molecules containing conformational rigidity, 14 containing benzo[4,5]furo[3,2-b]pyridine core and 15 comprising chromeno[4,3-b]pyridine core, were synthesized, and their biological activities were evaluated. 3-(4-Ph

Discovery of 3,3a,4,5-tetrahydro-2H-benzo[g]indazole containing quinoxaline derivatives as novel EGFR/HER-2 dual inhibitors

In the present study, twenty-five pyrazole-quinoxaline derivatives (4a-4y) were designed and synthesized, and their biological activity as potential EGFR or HER-2 kinase inhibitors was evaluated. Among them, compound 4l displayed better antiproliferative

Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase i and II inhibitory activity, cytotoxicity, and structure-activity relationship

Designed and synthesized were a series of 5H-chromeno[4,3-b]pyridines with substitution at 2- and 4-positions with various 5- or 6-membered heteroaromatics as antitumor agents. They were evaluated for topoisomerase I and II inhibitory activities as well a

Novel α-hydroxyphosphonates - Enol phosphates rearrangement

CsF was found to be a very efficient basic catalyst for the rearrangement of α-hydroxy-β,γ-epoxy(aziridino)phosphonates to enol phosphates. DBU and potassium fluorides (anhydrous or dihydrate) appeared less active in promoting this rearrangement, but strong enough to execute the retro-Abramov reaction. Because of the competition from the retro-Abramov reaction, stereochemistry of the rearrangement cannot be unequivocally assigned, but it seems reasonable that intermediates having the dimethoxy-phosphoryl group and O-epoxide or N-aziridine atoms as leaving groups in the antiperiplanar positions are involved.

Synthesis and conformational analysis of some spiropyrazoline isomers

A series of spiropyrazolines has been synthesized by 1,3-dipolar cycloaddition of E- and Z-3-arylidene-chromanones, -1-thiochromanones, -flavanones, -1-thioflavanones as well as 2-benzylidene-1-indanone, -1-benzosuberone with diazomethane. It has been found that this cycloaddition is regio- and stereoselective affording trans- and cis- spiro-1-pyrazolines. Spiro-1-pyrazolines were converted into spiro-2-pyrazolines on acid-catalysed isomerization. Conformation and relative configuration of compounds prepared has been elucidated by various one- and two-dimensional n.m.r. methods.