121809-57-2

Upstream product

• 67-66-3 chloroform 
• 2298-29-5 N-(4-hydroxyphenyl)-N'-phenylurea 
• 67-64-1 acetone 
• 103-71-9 phenyl isocyanate 
• 123-30-8 4-amino-phenol 
• 1609180-23-5 ethyl 2-{4-[(anilinocarbonyl)amino]phenoxy}-2-methylpropanoate 
• 121809-55-0 2-<4-<(ethoxycarbonyl)amino>phenoxy>-2-methylpropionic acid 
• 121809-54-9 2-(4-carbamoylphenoxy)-2-methylpropionic acid 
• 79925-16-9 2-(4-cyanophenoxy)-2-methylpropionic acid 
• 767-00-0 4-cyanophenol 
• 7159-95-7 (4-hydroxyphenyl)carbamic acid ethyl ester 
• 117011-70-8 2-(4-aminophenoxy)-2-methyl propionic acid 

Relevant academic research and scientific papers

Effect of stilbene and chalcone scaffolds incorporation in clofibric acid on PPARα agonistic activity

In an effort to develop safe and efficacious compounds for the treatment of metabolic disorders, new compounds based on a combination of clofibric acid, the active metabolite of clofibrate, and trans-stilbene, chalcone, and other lipophilic groups were synthesized. They were evaluated for PPARα transactivation activity; all branched derivatives showed an increase of the transcriptional activity of receptor compared to the linear ones. Noteworthy, stilbene and benzophenone branched derivatives activated the PPARα better than clofibric acid.

Synthesis and Investigation of Effects of 2-amino>phenoxy>-2-methylpropionic Acids on the Affinity of Hemoglobin for Oxygen: Structure-Activity Relationships

A series of 2-carbonyl>amino>phenoxy>-2-methylpropionic acids and other substituted phenoxyacetic acids were synthesized and tested for their ability to reduce the affinity of hemoglobin for oxygen. 2-4-(3,4,5-Trichloro