1218943-32-8

Basic information

• Product Name: trans-4-Trifluoromethyl-cyclohexylamine hydrochloride
• Synonyms: trans-4-Trifluoromethyl-cyclohexylamine hydrochloride;trans-4-(Trifluoromethyl)cyclohexan-1-amine hydrochloride
• CAS NO: 1218943-32-8
• Molecular Formula: C₇H₁₂F₃N*ClH
• Molecular Weight: 203.6330296
• Mol File: 1218943-32-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: trans-4-Trifluoromethyl-cyclohexylamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-Trifluoromethyl-cyclohexylamine hydrochloride(1218943-32-8)
• EPA Substance Registry System: trans-4-Trifluoromethyl-cyclohexylamine hydrochloride(1218943-32-8)

Safety Data

• Hazardous Substances Data: 1218943-32-8(Hazardous Substances Data)

Usage

General Description

Trans-4-Trifluoromethyl-cyclohexylamine hydrochloride is a chemical compound that belongs to the class of amines. It is a derivative of cyclohexylamine with a trifluoromethyl group attached to the fourth carbon atom. The hydrochloride salt form of this compound is commonly used in pharmaceutical research and drug development. It has potential applications in the synthesis of various bioactive compounds and as a building block in organic chemistry. This chemical is known for its unique properties and has gained attention for its potential therapeutic uses in the pharmaceutical industry.

Upstream product

• 933781-52-3 trans-4-(trifluoromethyl)cyclohexanecarboxamide 
• 934330-05-9 trans-4-(trifluoromethyl)cyclohexanecarbonyl chloride 
• 133261-33-3 trans-4-trifluoro-methyl-cyclohexanecarboxylic acid 

Downstream Products

• 1242270-09-2 N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-fluoro-4-methylamino-5-nitro-benzoic acid amide 
• 1360622-20-3 N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-{2,6-dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2,2-trifluoroethoxy)-7-fluoro-1H-benzimidazole-5-carboxylic acid amide 
• 1360622-01-0 N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-{2,6-dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoro-ethoxy)-1-methyl-1H-benzimidazole-5-carboxylic acid amide 
• 1242269-83-5 N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(2,2-difluoro-ethoxy)-4-methylamino-5-amino-benzoic acid amide 
• 1242270-11-6 N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(2,2-difluoro-ethoxy)-4-methylamino-5-nitro-benzoic acid amide 

Relevant articles and documents

NEW COMPOUNDS

This invention relates to compounds of formula (I) their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R6, R7, R8 have meanings given in the description.