121898-55-3

Upstream product

• 129098-50-6 (2R,4R)-2,4-dimethyl-1,5-dioxaspiro<5.5>undecane 
• 108-94-1 cyclohexanone 
• 42075-32-1 (2R,4R)-pentanediol 
• 72345-23-4 (2S,4S)-pentane-2,4-diol 

Downstream Products

• 374566-47-9 tert-Butyl-[(1R,3R)-3-(cyclohex-1-enyloxy)-1-methyl-butoxy]-dimethyl-silane 
• 189636-73-5 3-Oxo-butyric acid (1R,3R)-3-(cyclohex-1-enyloxy)-1-methyl-butyl ester 
• 36302-36-0 (1S)-ethyl (2-oxocyclohexyl)acetate 
• 189636-75-7 Diazo-acetic acid (1R,3R)-3-(cyclohex-1-enyloxy)-1-methyl-butyl ester 
• 533-60-8 (R)-α-hydroxycyclohexanone 
• 53439-93-3 (S)-α-hydroxycyclohexanone 
• 64363-90-2 (+)-(2R)-2-acetoxycyclohexanone 
• 13122-52-6 4-methoxy-pentan-2-one 
• 1448542-34-4 (2S,4R)-4-(cyclohex-1-en-1-yloxy)pentan-2-yl 4-methoxybenzoate 
• 1448542-30-0 (2S,4R)-4-(cyclohex-1-en-1-yloxy)pentan-2-ol 

Relevant academic research and scientific papers

DIASTEREO-DIFFERENTIATING CYCLOPROPANATION OF A CHIRAL ENOL ETHER: A SIMPLE METHOD FOR THE PREPARATION OF OPTICALLY PURE CYCLOPROPYL ETHERS

Enol ether of cyclohexanone carrying 2,4-pentanediol (PD) or 2,6-dimethyl-3,5-heptanediol (DMHD) as a chiral auxiliary was subjected to diastereo-differentiating cyclopropanation.The highest diastereomer excess (d.e.) of the product was found to be 95.2percent in the case of PD and over 99.5percent in the case of DMHD.The enol ethers prepared from various ketones and DMHD were also cyclopropanated in giving cyclopropyl ethers in almost 100percent d.e..

Stereospecific Cyclization of Vinyl Ether Alcohols. Facile Synthesis of (-)-Lardolure

An efficient and stereospecific ring formation from unsaturated alcohols, which in turn are prepared by regio- and stereospecific ring opening of acetals, is described.

DIASTEREO-DIFFERENTIATING SIMMONS-SMITH REACTION USING 2,4-PENTANEDIOL AS A CHIRAL AUXILIARY

Diastereo-differentiating Simmons-Smith reaction to (1'R,3'R,)-1-(3'-hydroxy-1'-methylbutyloxy)cyclohexene has been performed to give (1'R,3'R,1S,6S)-1-(3'-hydroxy-1'-methylbutyloxy)bicycloheptane in 95.2percent d. e..