121905-60-0 Usage
Description
M-Tolylmagnesium chloride, also known as 3-methylphenylmagnesium chloride, is a Grignard reagent that is widely used as a reagent in organic synthesis. It is a chemical compound consisting of a magnesium atom bonded to a carbon atom with a tolyl group, which is a methyl-substituted phenyl group. This versatile compound is capable of forming carbon-carbon bonds and reducing carbonyl compounds, making it a valuable tool in the synthesis of complex organic molecules. Due to its reactivity and sensitivity to air and moisture, M-tolylmagnesium chloride must be handled and used with caution.
Uses
Used in Pharmaceutical Industry:
M-Tolylmagnesium chloride is used as a reagent for the synthesis of complex organic molecules in the pharmaceutical industry. Its ability to form carbon-carbon bonds and reduce carbonyl compounds makes it a valuable tool in the development of new drugs and pharmaceutical compounds.
Used in Fine Chemical Industry:
In the fine chemical industry, M-tolylmagnesium chloride is employed as a reagent for the synthesis of complex organic molecules with specific properties and functions. Its versatility in forming carbon-carbon bonds and reducing carbonyl compounds allows for the creation of a wide range of specialty chemicals used in various applications, such as fragrances, dyes, and agrochemicals.
Used in Organic Synthesis:
M-Tolylmagnesium chloride is used as a Grignard reagent in organic synthesis for the formation of carbon-carbon bonds and the reduction of carbonyl compounds. This allows for the creation of a variety of organic compounds with different structures and properties, which can be further modified or functionalized to meet specific requirements in various industries.
Used in Academic Research:
In academic research, M-tolylmagnesium chloride is utilized as a reagent to explore new synthetic pathways, develop novel reactions, and study the mechanisms of organic transformations. Its unique reactivity and versatility make it an essential tool for chemists working in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 121905-60-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,9,0 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 121905-60:
(8*1)+(7*2)+(6*1)+(5*9)+(4*0)+(3*5)+(2*6)+(1*0)=100
100 % 10 = 0
So 121905-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H7.ClH.Mg/c1-7-5-3-2-4-6-7;;/h2-3,5-6H,1H3;1H;/q-1;;+2/p-1
121905-60-0Relevant articles and documents
Continuous preparation of arylmagnesium reagents in flow with inline IR monitoring
Brodmann, Tobias,Koos, Peter,Metzger, Albrecht,Knochel, Paul,Ley, Steven V.
experimental part, p. 1102 - 1113 (2012/08/27)
A newly developed microscale ReactIR flow cell was used as a convenient and versatile inline analytical tool for Grignard formation in continuous flow chemical processing. The LiCl-mediated halogen/Mg exchange reaction was used for the preparation of functionalized arylmagnesium compounds from aryl iodides or bromides. Furthermore, inline IR monitoring was used for the analysis of conversion and possible byproduct formation, as well as a potential tool for elucidation of mechanistic details. The results described herein indicate that the continuous flow systems are effective for highly exothermic reactions such as the Grignard exchange reaction due to fast mixing and efficient heat transfer.
