296776-75-5

Upstream product

• 121905-60-0 3-methylphenylmagnesium chloride 
• 81-07-2 saccharin 
• 28987-79-3 m-tolylmagnesium bromide 

Downstream Products

• 1356266-15-3 (E)-ethyl 2-(4,4-dioxido-8b-(m-tolyl)-1H-azeto[1,2-b]benzo[d]isothiazol-2(8bH)-ylidene)acetate 
• 1356266-36-8 ethyl 9b-(m-tolyl)-1,9b-dihydrobenzo[d]pyrrolo[1,2-b]isothiazole-3-carboxylate 5,5-dioxide 
• 1356266-27-7 ethyl 9b-(m-tolyl)-3,9b-dihydrobenzo[d]pyrrolo[1,2-b]isothiazole-1-carboxylate 5,5-dioxide 
• 296776-78-8 (S)-3-(m-tolyl)-2,3-dihydrobenzo[d]isothiazole-1,1-dioxide 

Relevant academic research and scientific papers

Efficient visible-light photocatalytic aerobic oxidation of cyclic sulfamides to imines

A highly efficient photocatalytic aerobic oxidation of cyclic sulfamides to synthesize cyclic N-sulfonyl imines with Ir(ppy)2(dtbpy)PF6 as photocatalyst is reported. These environmentally friendly transformations exihibit good to excellent isolated yields and good generality with respect to both five-membered and six-membered cyclic sulfamides.

Pd/Zn(OTf)2 Co-Catalyzed Asymmetric Hydrogenation of Imines under Normal Pressure of Hydrogen

An efficient method for the asymmetric hydrogenation of cyclic and acyclic N-sulfonylimines co-catalyzed by Pd/Zn(OTf)2 using hydrogen gas under ambient pressure was developed. The methodology offers an easy access to generate chiral sulfonylam

Iridium(III)-Catalyzed Selective and Mild C-H Amidation of Cyclic N-Sulfonyl Ketimines with Organic Azides

A general protocol for iridium catalyzed direct C?H amidation of cyclic N-sulfonyl ketimines using sulfonyl, acyl and aryl azides as nitrogen source is reported herein. The reaction takes place at room temperature with acyl and aryl azides, while an elevated temperature needed with sulfonyl azides to furnish aminated sultams in excellent yields with complete chemo and regioselectivity, thus providing a robust and environmentally benign process to the synthesis of aminosultams. (Figure presented.).

Formal palladium-catalyzed asymmetric hydrogenolysis of racemic N -sulfonyloxaziridines

Highly enantioselective palladium-catalyzed formal hydrogenolysis of racemic N-sulfonyloxaziridines has been realized, providing a novel access to sultams with up to 99% ee. Preliminary mechanistic insights revealed that the reaction proceeded through a N-O bond cleavage, dehydration, and the sequential asymmetric hydrogenation.

Sultams: catalyst systems for asymmetric reduction of a C=N intermediate biological compositions and methods for making the sultams

Biologically active sultams are disclosed which have potent anti-HIV activity. Solution methods of syntheses, which use a new catalyst for the asymmetric reduction of a C═N intermediate, are described. Biological compositions and method of treating mammal