1219130-57-0

Basic information

• Product Name: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one
• Synonyms: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one;3(4H)-Oxo-2H-benzo[b][1,4]oxazin-7-boronic acid pinacol ester;2H-1,4-benzoxazin-3(4H)-one, 7-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;7-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-3,4- dihydro-2H-1,4-benzoxazin-3-one;3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-boronic acid pinacol ester;7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-1,4-benzoxazin-3-one
• CAS NO: 1219130-57-0
• Molecular Formula: C14H18BNO4
• Molecular Weight: 275
• EINECS: 200-582-5
• Product Categories: Organic boronic acid
• Mol File: 1219130-57-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 444.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.20
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 12.80±0.20(Predicted)
• CAS DataBase Reference: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one(1219130-57-0)
• EPA Substance Registry System: 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one(1219130-57-0)

Safety Data

• Hazardous Substances Data: 1219130-57-0(Hazardous Substances Data)

Usage

General Description

The chemical "7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one" is a compound with a complex molecular structure. It contains a 1,3,2-dioxaborolan-2-yl group and a benzo[b][1,4]oxazin-3(4H)-one group. The presence of the dioxaborolan-2-yl group suggests that the compound is potentially useful for Suzuki-Miyaura cross-coupling reactions, a common method for forming carbon-carbon bonds in organic synthesis. The benzo[b][1,4]oxazin-3(4H)-one group indicates that the compound may have biological activity, as molecules with similar structures have been studied for their antimicrobial and anticancer properties. Further research is needed to fully understand the potential uses and properties of this chemical.

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 321436-06-0 7-bromo-3,4-dihydro-2H-1,4-benzoxazin-3-one 
• 38191-34-3 2-amino-5-bromophenol 
• 27684-84-0 5-bromo-2-nitrophenol 

Downstream Products

• 67193-97-9 7-hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 1489264-77-8 4-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-1,4-benzoxazin-3(4H)-one 

Relevant articles and documents

SYK INHIBITORS

The present disclosure a Syk compound inhibitors, including state cancer and inflammation and various disease States thereof in the treatment of relates to the use of. In one aspect a particular embodiment, . given by formula I which is marked as a chemical structure of compound. In formula said, X 1, X 2, X 3, R 2, R 3, R 4, R 5, and Y has described herein is. The present disclosure of a formula I compounds or a pharmaceutically acceptable salt of pharmaceutical compositions including, mediated by Syk and to treat conditions a employing these compounds and compositions further provides a method. (by machine translation)

HETEROCYCLIC BIARYL DERIVATIVE AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT

Novel heterocyclic biaryl derivatives were disclosed which are useful as pharmaceutical agents and which exhibit a phosphodiesterase-inhibitory action. The heterocyclic biaryl derivatives are represented by the following general formula (1): wherein the H