1220527-06-9

Basic information

• Product Name: 2-butyl-1-(trichloromethyl)-3-phenyl-1,2-dihydrobenzo[ b ][1,6]naphthyridine
• CAS NO: 1220527-06-9
• Molecular Weight: 431.792
• Mol File: 1220527-06-9.mol

Chemical Properties

• CAS DataBase Reference: 2-butyl-1-(trichloromethyl)-3-phenyl-1,2-dihydrobenzo[ b ][1,6]naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-butyl-1-(trichloromethyl)-3-phenyl-1,2-dihydrobenzo[ b ][1,6]naphthyridine(1220527-06-9)
• EPA Substance Registry System: 2-butyl-1-(trichloromethyl)-3-phenyl-1,2-dihydrobenzo[ b ][1,6]naphthyridine(1220527-06-9)

Safety Data

• Hazardous Substances Data: 1220527-06-9(Hazardous Substances Data)

Upstream product

• 868765-12-2 2-phenylethynyl-quinoline-3-carbaldehyde 
• 67-66-3 chloroform 
• 109-73-9 N-butylamine 
• 73568-25-9 2-chloro-3-quinoline carboxaldehyde 
• 536-74-3 phenylacetylene 

Relevant articles and documents

A facile and efficient synthesis of 1-trichloromethyl-1,2-dihydrobenzo [b] [1,6] naphthyridines via three-component reaction among 2-alkynylquinoline-3- carbaldehydes, primary amines, and chloroform

A three-component reaction among 2-alkynylquinoline-3-carbaldehydes, primary amines, and chloroform leading to novel 1-(trichloromethyl)-1,2- dihydrobenzo [b] [1,6] naphthyridines was developed using microwave initiation in an absence of any catalysts. Th

Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines

A series of 2-substituted 1,2-dihydro-3-phenyl-1-(trichloromethyl)benzo[b][1,6]naphthyridines were synthesized and their in vitro antiproliferative activities were examined against human solid tumor cell lines and relevant strains of bacteria and Candida.