1221408-65-6

Basic information

• Product Name: 4-(4-(2-methoxyphenyl)piperazin-1-yl)butan-1-amine hydrochloride
• Synonyms: 4-(4-(2-methoxyphenyl)piperazin-1-yl)butan-1-amine hydrochloride
• CAS NO: 1221408-65-6
• Molecular Weight: 299.844
• Mol File: 1221408-65-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-(2-methoxyphenyl)piperazin-1-yl)butan-1-amine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-(2-methoxyphenyl)piperazin-1-yl)butan-1-amine hydrochloride(1221408-65-6)
• EPA Substance Registry System: 4-(4-(2-methoxyphenyl)piperazin-1-yl)butan-1-amine hydrochloride(1221408-65-6)

Safety Data

• Hazardous Substances Data: 1221408-65-6(Hazardous Substances Data)

Upstream product

• 21103-33-3 4-[4-(2-methoxyphenyl)piperazin-1-yl]butylamine 
• 102392-05-2 2-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-isoindole-1,3-dione 

Downstream Products

• 21103-33-3 4-[4-(2-methoxyphenyl)piperazin-1-yl]butylamine 

Relevant articles and documents

Discovery of naphthalimide conjugates as fluorescent probes for α1-adrenoceptors

α1-Adrenoceptors (α1-ARs), including at least three subtypes, α1A, α1B and α1D, which play essential roles in G protein-coupled receptors (GPCRs), can convey multiple pivotal extracellular signals in varied tissues and organs. In this research, a series of napthalimide-based small-molecule fluorescent probes (1a–1f) for α1-ARs, including two parts, a pharmacophore (quinazoline and phenylpiperazine) for α1-AR recognition and a fluorophore (naphthalimide) for visualization, were designed and synthesized successfully. These compounds display excellent fluorescence property and high affinity to receptors, which were used successfully for in vitro visualization of α1-adrenoceptors.