122151-32-0 Usage
Description
1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine is a complex organic chemical compound that belongs to the class of organic compounds known as polypyrrolidones. It features a pyrrolidine core structure, which is a saturated five-membered nitrogen-containing ring, and a benzyl group. 1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine also contains an acyl group attached to the pyrrolidine part, indicating its carboxylic acid derivative characteristic. The stereochemistry of the molecule is denoted by the (2S) prefix, signifying that the compound has a chiral center with an 'S' configuration. Details about its physical properties, bioactivity, safety, or potential applications are typically specific to the context of its use or study.
Uses
Used in Pharmaceutical Industry:
1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure and stereochemistry make it a valuable building block in the development of new therapeutic agents.
Used in Chemical Research:
1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine is used as a research compound in the field of organic chemistry. Its complex structure and potential reactivity with other molecules make it an interesting subject for studying chemical reactions and mechanisms.
Used in Material Science:
1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine is used as a component in the development of new materials with specific properties. Its incorporation into polymers or other materials could lead to the creation of novel materials with unique characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 122151-32-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,1,5 and 1 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 122151-32:
(8*1)+(7*2)+(6*2)+(5*1)+(4*5)+(3*1)+(2*3)+(1*2)=70
70 % 10 = 0
So 122151-32-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H19NO2/c1-12(14(16)15-9-5-6-10-15)17-11-13-7-3-2-4-8-13/h2-4,7-8,12H,5-6,9-11H2,1H3/t12-/m0/s1
122151-32-0Relevant articles and documents
Efficient Stereoselective Synthesis of a Key Chiral Aldehyde Intermediate in the Synthesis of Picolinamide Fungicides
Li, Fangzheng,Good, Steffen,Tulchinsky, Michael L.,Whiteker, Gregory T.
, p. 2253 - 2260 (2019)
A highly stereoselective and efficient synthesis of (4S,5S,6S)-6-(benzyloxy)-5-phenoxy-4-propoxyheptanal, a key intermediate for syntheses of picolinamide fungicides, is described in this report. The synthesis features a scalable allylpropyl ether preparation, an efficient synthesis of the C1-C3 anti,syn-(S,S,S) stereotriad via a highly diastereoselective allylboration, and Cu-catalyzed phenylation of a sterically hindered secondary alcohol with BiPh3(OAc)2 followed by highly regioselective hydroformylation with the formation of a linear aldehyde. Excellent overall route efficiency was achieved (six steps and 39% yield) starting from readily available and inexpensive (S)-ethyl lactate.
Toward Chromanes by de Novo Construction of the Benzene Ring
Geist, Egor,Berneaud-K?tz, Helge,Baikstis, Tomas,Dr?ger, Gerald,Kirschning, Andreas
supporting information, p. 8930 - 8933 (2019/11/14)
The work describes three principal Diels-Alder cycloaddition approaches toward chromanes that are designed for the de novo construction of the benzene ring. This study specifically focuses on the potential exploitation in the total synthesis of chromane-bearing natural products such as cebulactam A.
Stereoselective titanium-mediated aldol reactions of α-benzyloxy methyl ketones
Pellicena, Miquel,Solsona, Joan G.,Romea, Pedro,Urpi, Felix
, p. 10338 - 10350,13 (2012/12/12)
Good levels of 1,4-anti asymmetric induction are obtained in the TiCl 3(i-PrO)-mediated aldol reaction of chiral α-benzyloxy methyl ketones with a wide array of aldehydes. This methodology represents a new approach to substrate-controlled acetate aldol reactions capable of providing highly functionalized fragments in a straightforward manner, which may be useful in the design of more efficient syntheses.