1221740-99-3Relevant academic research and scientific papers
Tandem phenolic oxidative amidation-intramolecular diels-alder reaction: An approach to the himandrine core
Liang, Huan,Ciufolini, Marco A.
supporting information; experimental part, p. 1760 - 1763 (2010/10/21)
An oxidative cyclization of dienic sulfonamides mediated by iodobenzene diacetate in TFA, followed by a tandem intramolecular Diels-Alder reaction, achieves desymmetrization of a "locally symmetrical" dienone with good levels of diastereoselectivity and leads to valuable synthetic intermediates for the himandrine alkaloids.
Oxidative spirocyclization of phenolic sulfonamides: Scope and applications
Liang, Huan,Ciufolini, Marco A.
supporting information; experimental part, p. 13262 - 13270 (2011/03/17)
A full account of the oxidative dearomatization of para- and ortho-phenolic sulfonamides is provided together with an overview of the chemistry of the products and their elaboration to building blocks for spirocyclic alkaloids. A concise total synthesis of putative lepadiformine complements the discussion. Making building blocks: The oxidative dearomatization of para- and ortho-phenolic sulfonamides provides building blocks for spirocyclic alkaloids (see scheme). The chemistry of the products of this reaction and a concise total synthesis of putative lepadiformine is given.
