122245-79-8

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 98253-69-1 2-(trimethylsilyloxy)acrylic acid ethyl ester 
• 67-56-1 methanol 
• 100-52-7 benzaldehyde 

Downstream Products

• 1309647-65-1 C₁₃H₁₇NO₄ 
• 17451-20-6 (E)-ethyl-2-oxo-4-phenylbut-3-enoate 

Relevant academic research and scientific papers

The Boron Trifluoride Catalyzed Aldol Reaction of Methyl 2-(Trimethylsiloxy)acrylate with Aldehydes in the Presence of Alcohols

The boron trifluoride etherate catalyzed aldol reaction of methyl 2-(trimethylsiloxy)acrylate with aldehydes proceeded smoothly in the presence of primary, secondary and tertiary alcohol to give corresponding γ-alkoxy-α-ketoesters.

A New Synthetic Method for α-Oxo-β,γ-unsaturated Esters

α-Oxo-β,γ-unsaturated esters have been prepared in moderate to good yields via a two-step procedure consisting of the boron trifluoride-promoted reaction of 2-(trimethylsiloxy)acrylic esters with acetals, followed by treatment with silics gel in benzene u

Catalytic synthesis of γ-alkoxy-α-keto esters

Copper(II) triflate effectively catalyzes the reaction of (trimethylsilyloxy)acrylic esters and acetals to form -alkoxy - keto esters. The reaction proceeds under mild conditions providing products in good to excellent yields. The substrate scope was investigated, and it was demonstrated that the products could be converted into related compounds such as γ-hydroxy -α- keto esters and α-oximes. Georg Thieme Verlag Stuttgart - New York.