122252-52-2

Upstream product

• 65300-29-0 (E)-4-(4-fluorophenyl)but-3-en-2-one 
• 105-45-3 acetoacetic acid methyl ester 
• 65300-29-0 4-(4-fluorophenyl)but-3-en-2-one 

Downstream Products

• 123930-14-3 (E)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2(R)-methoxy-3,4,5,6-tetrahydro-2H-pyran 
• 123930-32-5 (Z)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2(R)-methoxy-3,4,5,6-tetrahydro-2H-pyran 
• 122253-84-3 (E)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2-hydroxy-3,4,5,6-tetrahydro-2H-pyran 
• 122253-84-3 (Z)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2-hydroxy-3,4,5,6-tetrahydro-2H-pyran 
• 122254-03-9 (E)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-3,4,5,6-tetrahydro-2H-pyran-2-one 
• 122287-18-7 (Z)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-3,4,5,6-tetrahydro-2H-pyran-2-one 
• 122253-42-3 <2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>methyltriphenylphosphonium bromide 
• 122252-96-4 2,6-Dimethyl-4-(4-fluorophenyl)-3-hydroxymethyl-pyridine 
• 122253-19-4 bromo<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>methane 
• 122252-67-9 methyl 2,6-dimethyl-4-(4-fluorophenyl)-pyridine-3-carboxylate 

Relevant academic research and scientific papers

3-demethylmevalonic acid derivatives, and pharmaceutical products based on these compounds

3-Demethylmevalonic acid derivatives of the formula I (δ-lactone) and II (corresponding dihydroxy carboxylic acid derivative) STR1 in which A--B, Z, R1, R2, R3 and R4 have the indicated meanings, a process for t

Synthesis and Biological Activity of New HMG-CoA Reductase Inhibitors. 1. Lactones of Pyridine- and Pyrimidine-Substituted 3,5-Dihydroxy-6-heptenoic (-heptanoic) Acids

Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids 2-4 have been synthesized.Extensive exploration of structure-activity relationships led to several compounds exceeding the inhibitory activity of mevinolin (1b)