122252-67-9

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 65300-29-0 4-(4-fluorophenyl)but-3-en-2-one 
• 122252-52-2 3-(4-fluorophenyl)-2-(1-oxoethyl)-5-oxohexanoic acid methyl ester 

Downstream Products

• 123930-14-3 (E)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2(R)-methoxy-3,4,5,6-tetrahydro-2H-pyran 
• 123930-32-5 (Z)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2(R)-methoxy-3,4,5,6-tetrahydro-2H-pyran 
• 122253-84-3 (E)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2-hydroxy-3,4,5,6-tetrahydro-2H-pyran 
• 122253-84-3 (Z)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-2-hydroxy-3,4,5,6-tetrahydro-2H-pyran 
• 122254-03-9 (E)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-3,4,5,6-tetrahydro-2H-pyran-2-one 
• 122287-18-7 (Z)-4(R)-<(tert-butyldiphenylsilyl)oxy>-6(S)-<2-<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>ethenyl>-3,4,5,6-tetrahydro-2H-pyran-2-one 
• 122253-42-3 <2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>methyltriphenylphosphonium bromide 
• 122253-19-4 bromo<2,6-dimethyl-4-(4-fluorophenyl)pyridin-3-yl>methane 
• 122252-96-4 2,6-Dimethyl-4-(4-fluorophenyl)-3-hydroxymethyl-pyridine 

Relevant academic research and scientific papers

7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis

Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula STR1 in which A, B, D and E can have varied meanings, X is --CH2 --CH2 or --CH=CH--, and R is STR2 wherein R21 denotes hyd

CERTAIN 7-[2,6-DIISOPROPYL-4-PHENYL-5-LOWER ALKOXYMETHYL-PYRID-3-YL]-3,5-DIHYDROXY-6-ENOATES AND DERIVATIVES USEFUL FOR TREATING CIRCULATORY DISEASES

Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula (I) in which A, B, D and E can have varied meanings, X is -CH2-CH2 or -CH=CH-, and R is wherein R21 denotes hydrogen or alkyl and R22 denotes hydrogen, denotes alkyl, aryl or aralkyl, or denotes a cation, and their oxidation products

Synthesis and Biological Activity of New HMG-CoA Reductase Inhibitors. 1. Lactones of Pyridine- and Pyrimidine-Substituted 3,5-Dihydroxy-6-heptenoic (-heptanoic) Acids

Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids 2-4 have been synthesized.Extensive exploration of structure-activity relationships led to several compounds exceeding the inhibitory activity of mevinolin (1b)