1222831-62-0

Basic information

• Product Name: 2-chloro-N-(3-(3-fluorophenyl)-4-methylthiazol-2(3H)-ylidene)benzamide
• CAS NO: 1222831-62-0
• Molecular Weight: 346.812
• Mol File: 1222831-62-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-chloro-N-(3-(3-fluorophenyl)-4-methylthiazol-2(3H)-ylidene)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-(3-(3-fluorophenyl)-4-methylthiazol-2(3H)-ylidene)benzamide(1222831-62-0)
• EPA Substance Registry System: 2-chloro-N-(3-(3-fluorophenyl)-4-methylthiazol-2(3H)-ylidene)benzamide(1222831-62-0)

Safety Data

• Hazardous Substances Data: 1222831-62-0(Hazardous Substances Data)

Upstream product

• 1208231-02-0 1-(2-chlorobenzoyl)-3-(3-fluorophenyl)thiourea 
• 67-64-1 acetone 
• 598-31-2 1-bromoacetone 

Relevant articles and documents

Distinctive inhibition of alkaline phosphatase isozymes by thiazol-2-ylidene-benzamide derivatives: Functional insights into their anticancer role

In the recent years, the role of alkaline phosphatase (AP) isozymes in the cause of neoplastic diseases such as breast, liver, renal, and bone cancer has been confirmed and, thus they represent a novel target for the discovery of anticancer drugs. In this

Synthesis and antimicrobial activity of some novel 2-(substituted fluorobenzoylimino)-3-(substituted fluorophenyl)-4-methyl-1,3-thiazolines

The synthesis of several 2-(substituted fluorobenzoylimino)-3-(substituted fluorophenyl)-4-methyl-1,3-thiazolines (2a-t) was carried out by base-catalyzed cyclization of corresponding 1-(fluorobenzoyl)-3-(fluorophenyl)thioureas (1a-t) with 2-bromoacetone in aqueous medium. The structures of the synthesized compounds were confirmed by spectral and elemental analysis. All synthesized compounds were evaluated for in vitro antibacterial activity using Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis) and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa). The minimum inhibitory concentration (MIC) was determined for the most active compounds. In vitro antifungal activity was also determined against the five fungal species (Rhizopus oryzae, Fusarium oxysporum, Aspergillus terreus, A. niger and A. fumigatus).