393-79-3Relevant articles and documents
Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound
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Paragraph 0044-0046, (2020/12/29)
The invention relates to a preparation method of 3, 5-dichloro-4-fluorobromobenzene. The method takes 2, 6-dichlorofluorobenzene as a raw material, the raw material is simple and easy to obtain, the cost is low, the method is simple in process, mild in condition and environment-friendly, the separation and purification of an intermediate product 2, 4-dichloro-3-fluoronitrobenzene through a crystallization method are much more efficient than those of the traditional distillation means, and the process safety is high. The loss is lower.
Preparation method of 2, 3, 4-trifluoronitrobenzene
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Paragraph 0011, (2019/05/15)
The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of 2, 3, 4-trifluoronitrobenzene. The method comprises the following steps: reacting 2,6-dichlorofluorobenzene as a raw material with HNO3/H2SO4 so as to obtain 2, 6-dichloro-3-nitrofluorobenzene, and then reacting the 2, 6-dichloro-3-nitrofluorobenzene with anhydrous potassium fluoride to obtain the 2, 3, 4-trifluoronitrobenzene. The method disclosed by the invention is high in yield, simple in synthesis and suitable for industrial production.