122412-14-0

Basic information

• Product Name: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate
• Synonyms: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate
• CAS NO: 122412-14-0
• Molecular Weight: 468.417
• Mol File: 122412-14-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate(122412-14-0)
• EPA Substance Registry System: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate(122412-14-0)

Safety Data

• Hazardous Substances Data: 122412-14-0(Hazardous Substances Data)

Upstream product

• 99815-16-4 3,4-bis(tert-butyldimethylsilanyloxy)benzaldehyde 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 1261480-13-0 (-)-epigallocatechin-3-gallate octa(tert-butyldimethylsilyl) ether 

Downstream Products

• 331-39-5 caffeic acid 
• 970-73-0 epigallocatechin 

Relevant articles and documents

Preparation method and application of hydroxyl cinnamyl ester type catechin

The invention relates to a preparation method and application of hydroxyl cinnamyl ester type catechins. The hydroxyl cinnamyl ester type catechins comprise four catechins which are respectively namedas epicatechin trans-coumarate, epicatechin trans-caffeic acid ester, epigallocatechin trans-coumarate and epigallocatechin trans-caffeic acid ester. The hydroxyl cinnamyl ester type catechins are prepared by the following steps: carrying out four steps of full acetylation on epicatechin and epigallocatechin, removal of acetyl on phenolic hydroxyl, silanizing of phenolic hydroxyl and removal of 3-acetyl, then respectively esterifying with acetylated caffeic acid or coumaric acid acyl chloride, and removing a protecting group. The preparation method of the four catechins is simple and mild inconditions, and can be completed under general experimental conditions. The four hydroxycinnamyl ester type catechins have a certain inhibition effect on the activity of alpha-glucosidase, can be usedfor hypoglycemic drugs, and have important significance in the fields of agriculture and medicine.

Caffeic acid derivatives in the treatment of leucoderma application (by machine translation)

The invention provides a coffee acid derivatives, the caffeic acid and derivatives with ester bond with the EGC connect into a prodrug, through the coffee acid and the EGC joint play activity, bioavailability is high, good treatment effect to vitiligo. (by machine translation)