122422-20-2Relevant academic research and scientific papers
Advances in the cobalt-catalysed Pauson-Khand reaction: Development of a sulfide-promoted, microwave-assisted protocol
Cochrane, Alison R.,Kerr, William J.,Paterson, Laura C.,Pearson, Colin M.,Shaw, Paul
, (2021)
The development of a sulfide-promoted, microwave-assisted Pauson-Khand reaction has enabled the formation of fused cyclopentenones using sub-stoichiometric quantities of a cobalt mediator over rapid reaction times and with no requirement for an external source of toxic carbon monoxide gas. This protocol displays applicability to both intra- and intermolecular Pauson-Khand reaction examples.
Optically Active Transition-Metal Complexes. 102. Enantioselective Synthesis of 3-Oxabicyclooct-7-en-7-phenyl-6-on via Khand-Pauson Reaction
Brunner, Henri,Niedernhuber, Alwin
, p. 711 - 714 (1990)
3-Oxabicyclooct-7-en-7-phenyl-6-on is obtained in the enantioselective Khand-Pauson reaction of (-)546-Co2(CO)5(PhC2H)(GLYPHOS), GLYPHOS = (R)-(+)-2,3-O-isopropylidenglycerol-1-diphenylphosphane with 2,5-dihydrofuran.Complete resolution
Promotion of the Pauson-Khand reaction using high intensity ultrasound
Ford,Kerr,Kirk,Lindsay,Middlemiss
, p. 1415 - 1418 (2007/10/03)
The use of a high powered ultrasound source in promoting the Pauson-Khand reaction has been extensively investigated. In conjunction with amines and N-oxide techniques, this developed methodology allows efficient access to a range of cyclopentenones in rapid reaction times and good to excellent yields.
The effect of ultrasound and of phosphine and phosphine-oxides on the Khand reaction
Billington, David C.,Helps, I. Malcolm,Pauson, Peter L.,Thomson, William,Willison, Debra
, p. 233 - 242 (2007/10/02)
Ultrasonic irradation allows the Khand reaction to be conducted rapidly at low temperatures.Addition of phosphine oxides to the reaction mixture significantly increases yields in most cases.
