122427-55-8

Basic information

• Product Name: 5-(2'-methoxy-4'-methylphenyl)hexanoic acid
• CAS NO: 122427-55-8
• Molecular Weight: 236.311
• Mol File: 122427-55-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-(2'-methoxy-4'-methylphenyl)hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2'-methoxy-4'-methylphenyl)hexanoic acid(122427-55-8)
• EPA Substance Registry System: 5-(2'-methoxy-4'-methylphenyl)hexanoic acid(122427-55-8)

Safety Data

• Hazardous Substances Data: 122427-55-8(Hazardous Substances Data)

Upstream product

• 143251-73-4 5-(2-Methoxy-4-methyl-phenyl)-hex-5-enoic acid 
• 71841-57-1 3-(o-methoxy-p-tolyl)-1-butanol 
• 76337-09-2 3-(2'-methoxy-4'-methylphenyl)butanal 
• 86525-77-1 3-(2'-methoxy-4'-methylphenyl)butanoic acid 
• 108-39-4 3-methyl-phenol 
• 4642-35-7 5-(2-hydroxy-4-methylphenyl)-5-oxopentanoic acid 
• 29207-19-0 methyl 5-(2-methoxy-4-methylphenyl)-5-oxopentanoate 
• 63023-50-7 methyl 5-(2-hydroxy-4-methylphenyl)-5-oxopentanoate 
• 108-55-4 glutaric anhydride, 
• 155608-76-7 Toluene-4-sulfonic acid 4-(2-methoxy-4-methyl-phenyl)-pentyl ester 
• 170235-81-1 1-iodo-4-(2'-methoxy-4'-methylphenyl)pentane 
• 170235-80-0 methyl 4-(2'-methoxy-4'-methylphenyl)-5-tosyloxypentanoate 
• 164921-74-8 methyl 4-(2'-methoxy-4'-methylphenyl)-5-hydroxy-(2E)-pentanoate 
• 170235-79-7 5-Hydroxy-4-(2-methoxy-4-methyl-phenyl)-pentanoic acid methyl ester 

Downstream Products

• 122427-58-1 4-(2'-methoxy-4'-methylphenyl)-n-pentyldimethylcarbinol 
• 66879-51-4 2-methoxy-4-methyl-1-(6-methylhept-5-en-2-yl)benzene 
• 71306-08-6 8-Methoxycalamenene 
• 170235-83-3 methyl-5-(2'-hydroxy-4'-methylphenyl)hexanoate 
• 76337-12-7 methyl 5-(2'-methoxy-4'-methylphenyl)hexanoate 
• 122427-49-0 5-(2-Hydroxy-4-methyl-phenyl)-hexanoic acid 

Relevant articles and documents

Reaction of methyl 4,5-epoxy-(2E)-pentenoate with arenes. II. Application to the synthesis of(±)-curcudiol, (±)-curcuphenol, (±)-curcuhydroquinone, and(±)-curcuquinone

Four bisabolane sesquiterpenes, (±)-curcudiol (2), (±)-curcuphenol (3), (±)-curcuhydroquinone (5) and (±)-curcuquinone (6), were synthesized based on the reaction of methyl 4,5-epoxy-(2E)-pentenoate (1) with methoxytoluenes in the presence of boron trifluoride etherate.

Synthesis of curcuphenol methyl ether and 8-methoxycalamenene

Friedel-Craft's acylation of m-cresol with glutaric anhydride, followed by esterification gives methyl 5-(2-hydroxy-4-methylphenyl)-5-oxopentanoate (4).Methylation of 4 followed by inverse Grignard reaction with methylmagnesium iodide yields an unsaturate