1224441-84-2Relevant academic research and scientific papers
A novel strategy for the construction of functionalized 1,5-benzodiazepines via a tandem conjugated addition/cyclization process
Li, Jian,Li, Shaoyu,Li, Chunju,Liu, Yuejin,Jia, Xueshun
, p. 336 - 340 (2010)
A novel approach for the synthesis of functionalized 1,5-benzodiazepine is described. The protocol is triggered by a tandem conjugated addition/ cyclization process from the readily available starting materials 1,2-phenylenediamine and ethyl propiolate. The products have secondary amino and ester groups, and a β-enamino ester, which can serve in further functionalizations to produce molecular diversity.
