1224568-02-8

Basic information

• Product Name: (R)-3-(1-(naphthalen-1-yl)ethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol
• Synonyms: (R)-3-(1-(naphthalen-1-yl)ethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol
• CAS NO: 1224568-02-8
• Molecular Weight: 373.418
• Mol File: 1224568-02-8.mol

Chemical Properties

• CAS DataBase Reference: (R)-3-(1-(naphthalen-1-yl)ethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-(1-(naphthalen-1-yl)ethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol(1224568-02-8)
• EPA Substance Registry System: (R)-3-(1-(naphthalen-1-yl)ethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol(1224568-02-8)

Safety Data

• Hazardous Substances Data: 1224568-02-8(Hazardous Substances Data)

Upstream product

• 82572-04-1 (R)-<1-(1-Naphthyl)ethyl>ammonium chloride 
• 349-76-8 3'-(trifluoromethyl)acetophenone 
• 1224567-99-0 3-{[(1R)-1-(naphthalen-1-yl)ethyl]amino}-1-[3-(trifluoromethyl)phenyl]propan-1-one hydrochloride 

Downstream Products

• 955373-56-5 (2E)-N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]prop-2-en-1-amine 
• 364782-34-3 cinacalcet hydrochloride 
• 1273259-52-1 (R)-3-chloro-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride 

Relevant articles and documents

PROCESS FOR PREPARING CINACALCET

A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula hydrochloride salt of formula (I); i.e. Cinacalcet.HC1 and its intermediate of formula (IX).

PROCESS FOR PREPARING CINACALCET

A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula (I) i.e. Cinacalcet and its intermediates of formulae (V), (Va) and (Vb).