1224640-11-2Relevant academic research and scientific papers
2-Phenoxy-nicotinamides are Potent Agonists at the Bile Acid Receptor GPBAR1 (TGR5)
Martin, Rainer E.,Bissantz, Caterina,Gavelle, Olivier,Kuratli, Christoph,Dehmlow, Henrietta,Richter, Hans G. F.,ObstSander, Ulrike,Erickson, Shawn D.,Kim, Kyungjin,Pietranico-Cole, Sherrie Lynn,Alvarez-Sanchez, Ruben,Ullmer, Christoph
, p. 569 - 576 (2013)
Potency with potential: 2-Phenoxy- nicotinamides were identified as potent agonists at the GPBAR1 receptor, a target in the treatment of obesity, type2 diabetes and metabolic syndrome. Extensive structure-activity relationship studies supported by homolog
