1225352-17-9

Upstream product

• 680-15-9 2,2-difluoro-2-(fluorosulfonyl)acetate 
• 1225352-13-5 6-bromo-2-(trans-4-tert-butylcyclohexyloxy)-1-iodonaphthalene 
• 937-05-3 cis-4-tert-butyl-1-cyclohexanol 
• 1225352-09-9 2-bromo-6-(trans-4-tert-butylcyclohexyloxy)naphthalene 
• 18508-90-2 trans-4-tert-butylmesyloxycyclohexane 
• 18508-91-3 methanesulfonic acid 4-tert-butylcyclohexyl ester 
• 15231-91-1 6-bromo-naphthalen-2-ol 

Downstream Products

• 1266115-96-1 1-((6-(trans-4-tert-butylcyclohexyloxy)-5-(trifluoromethyl)naphthalen-2-yl)methyl)azetidine-3-carboxylic acid 
• 1266115-94-9 methyl 1-((6-(trans-4-tert-butylcyclohexyloxy)-5-(trifluoromethyl)naphthalen-2-yl)methyl)azetidine-3-carboxylate 
• 1266115-65-4 3-((6-(trans-4-tert-butylcyclohexyloxy)-5-(trifluoromethyl)naphthalen-2-yl)methylamino)-N-(phenylsulfonyl)propanamide 
• 1266118-92-6 2-{[6-(trans-4-tert-butyl-cyclohexyloxy)-5-trifluoromethyl-naphthalen-2-ylmethyl]-amino}-ethanesulfonic acid 

Relevant academic research and scientific papers

COMPOUNDS THAT ARE S1P MODULATING AGENTS AND/OR ATX MODULATING AGENTS

Compounds of formula (I) can modulate the activity of one or more S1P receptors and/or the activity of autotaxin (ATX).

BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS

Compounds that have agonist activity at one or more of the SlP receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at SlP receptors.