1226-99-9

Basic information

• Product Name: 2-(benzoylthio)ethyl benzoate
• Synonyms: 2-(benzoylthio)ethyl benzoate
• CAS NO: 1226-99-9
• Molecular Weight: 286.351
• Mol File: 1226-99-9.mol

Chemical Properties

• CAS DataBase Reference: 2-(benzoylthio)ethyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzoylthio)ethyl benzoate(1226-99-9)
• EPA Substance Registry System: 2-(benzoylthio)ethyl benzoate(1226-99-9)

Safety Data

• Hazardous Substances Data: 1226-99-9(Hazardous Substances Data)

Upstream product

• 60759-50-4 3-acyl-2-oxazolone(R=Ph) 
• 60-24-2 2-hydroxyethanethiol 
• 99218-00-5 1,6-Diphenyl-2,7,8-trioxa-5-thia-bicyclo[4.2.0]octane 
• 98-88-4 benzoyl chloride 
• 155164-66-2 2-benzoyl-4,5-dichloropyridazin-3(2H)-one 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 58041-19-3 5,6-diphenyl-2,3-dihydro-1,4-oxathiin 

Relevant articles and documents

Facile esterification of alcohols with 2-Acyl-4,5-dichloropyridazin-3(2 H)-ones under Friedel-Crafts conditions

This paper describes the esterification of aromatic and aliphatic alcohols by using 2-acyl-4,5-dichloropyridazin-3(2H)-ones as an acyl source under Friedel-Crafts conditions. Twelve alcohols were reacted with four 2-acyl-4,5-dichloropyridazin-3(2H)-ones in the presence of AlCl3 in tetrahydrofuran at room temperature to give the corresponding esters in moderate to excellent yields. Thus, 2-acylpyridazin-3(2H)-ones serve as good and atom-economic acyl sources for the esterification of aromatic alcohols under Friedel-Crafts conditions, representing a rapid, practical, and efficient method of esterification. Georg Thieme Verlag Stuttgart. New York.

Rapid and Ecofriendly Esterification of Alcohols with 2-Acylpyridazinones

Atom-economical esterification is of great importance in green chemistry. In this work, we demonstrated the catalyst and additive free esterification of alcohols by their reaction with 2-acyl-4,5-dichloropyridazin-3(2H)- ones without solvent at 100 oC. Aliphatic and aromatic alcohols were converted into the corresponding esters in good to excellent yields. It is noteworthy that the reaction is solvent-free, atom-economic, easy-workup, and rapid and that the process is inexpensive.

EFFECTS OF HETEROATOM SUBSTITUENTS ON THE PROPERTIES OF 1,2-DIOXETANES

Nitrogen and sulfur-substituted dioxetanes exhibit dramatically lower activation energies for decomposition compared to the corresponding oxygen-bearing dioxetane.A mechanism involving intramolecular electron-transfer processes is proposed for the cleavage of these unstable dioxetanes.

ACTIVATION OF CARBOXYL GROUPS BY DIPHENYL 2-OXO-3-OXAZOLINYLPHOSPHONATE. FACILE PREPARATION OF VERSATILE REAGENTS, 3-ACYL-2-OXAZOLONES

Synthetic utility of the 2-oxazolone moiety as an excellent new leaving group is described.Based on such a function of the heterocycles, diphenyl 2-oxo-3-oxazolinylphosphonate has been newly introduced as a carboxyl-activating reagent which permits a facile direct preparation of 3-acyl-2-oxazolones and amides including peptides from a wide variety of carboxylic acids.The 3-acyl-2-oxazolides also serve as versatile reactive agents for highly chemoselective acyl-transfer to the nucleophilic species such as amines, alcohols and thiols, providing convenient and high-yield routes to amides, esters and thiol esters under mild conditions.They are also useful intermediates for ketones and alcohols.