1226154-84-2

Usage

Chemical Group

Piperidinols

Usage

Development of pharmaceutical drugs
Building block in organic synthesis

Therapeutic Effects

Analgesic (pain relief)
Antipsychotic (treatment of mental disorders)

Potential Applications

Treatment of neurological disorders
Target for drug discovery

Chemical Properties and Reactivity

Studied for its properties and reactivity
Importance in medicinal and organic chemistry
These properties and specific content provide a comprehensive overview of 1-(4-bromophenyl)-4-piperidinol, highlighting its chemical structure, applications, and significance in the fields of pharmaceuticals and organic chemistry.

Upstream product

• 589-87-7 1,4-bromoiodobenzene 
• 1380288-25-4 4-hydroxypiperidin-1-yl benzoate 
• 183677-71-6 2-(4-bromophenyl)-5,5-dimethyl-1,3,2-dioxaborinane 
• 154913-23-2 1-(4-bromophenyl)piperidin-4-one 
• 177-11-7 4,4-ethylenedioxy-piperidine 
• 142752-12-3 4-(4-hydroxypiperidin-1-yl)aniline 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 1415794-29-4 2-(1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidin-4-yloxy)ethanol 
• 1415794-28-3 2-(1-(4-bromophenyl)piperidin-4-yloxy)ethanol 
• 1415794-27-2 tert-butyl 2-(1-(4-bromophenyl)piperidin-4-yloxy)acetate 
• 1430472-07-3 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidin-4-ol 

Relevant academic research and scientific papers

Practical catalytic method for synthesis of sterically hindered anilines

A practical catalytic method for the synthesis of sterically hindered anilines is described. The amination of aryl and heteroaryl boronic esters is accomplished using a catalyst prepared in situ from commercially available and air-stable copper(i) triflat

NEW AZABENZIMIDAZOLE DERIVATIVES

The present invention relates to compounds of general formula I, wherein the group R1, R2, X, Y and z are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the AMP-activated protein kinase (AMPK) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

AZABENZIMIDAZOLE DERIVATIVES

The present invention relates to compounds of general formula (I), wherein the group R1, R2, X, Y and z are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the AMP-activated protein kinase (AMPK) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS

Provided are pyridopyrazine compounds of formula (1), pharmaceutical compositions thereof and methods of use therefore, wherein R1, R2, R3, R4 and m are as defined in the specification.