1226801-75-7Relevant academic research and scientific papers
Synthesis of (2-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-2-piperidin-4-yl-1 H-imidazol-1-yl}ethyl)dimethylamine
Vaid, Radhe K.,Boini, Sathish,Spitler, Jeremy T.,Pu, Yangwei John,May, Scott A.,Yu, Hannah,Sizhong, Wu,Fu, Jie,Zhang, Guoliang
, p. 1534 - 1540 (2013)
An efficient eight-step synthesis of the title compound, starting from oxoacetic acid monohydrate, was developed. Condensation of oxoacetic acid monohydrate with N,N-dimethylethanamine followed by reductive amination and protection gave N-(tert-butoxycarb
AKT AND P70 S6 KINASE INHIBITORS
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Page/Page column 25, (2010/06/11)
The present invention provides AKT and p70 S6 kinase inhibitors of the formula: The present invention also provides pharmaceutical compositions comprising compounds of Formula I, uses of compounds of Formula I and methods of using compounds of Formula I.
