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Upstream product

• 932-88-7 1-iodo-2-phenylethyne 
• 17061-86-8 1-methoxy-4-(2-propynyloxy)benzene 
• 622-79-7 benzyl azide 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

Highly Efficient Ultrasonic-Assisted CuCl-Catalyzed 1,3-Dipolar Cycloaddition Reactions in Water: Synthesis of Coumarin Derivatives Linked with 1,2,3-Triazole Moiety

By introducing ultrasound irradiation into “on water” CuCl-catalyzed 1,3-dipolar Huisgen cycloaddition, the reaction efficiencies were notably promoted toward a wide variety of applicable azides and alkynes at room temperature, and a series of coumarin de

Ligand Synthesis Catalyst and Complex Metal Ion: Multicomponent Synthesis of 1,3-Bis(4-phenyl-[1,2,3]triazol-1-yl)-propan-2-ol Copper(I) Complex and Application in Copper-Catalyzed Alkyne-Azide Cycloaddition

A new bistriazole copper complex was synthesized by direct treatment of an alkyne, an azide, and CuI as copper salt through in situ ligand formation under a multicomponent reaction process. This complex was analyzed by XPS, TGA, DSC, and SEM techniques an

Catalytic activity of dithioic acid copper complexes in the alkyne-azide cycloaddition

Diverse dithioic acid copper complexes exhibit a high catalytic activity in the copper-catalyzed alkyne-azide cycloaddition using several solvents under different temperatures, showing a high efficiency with only 0.005 mmol catalyst/mmol alkyne or less. A dithioic acid copper complex derived from acetophenone was selected and used as the catalyst in the preparation of a library of 1,4-disubstituted-1,2,3-triazoles. This process occurred in high yields and good functional group tolerance.

Alkyne-azide cycloaddition catalyzed by Fe-Cu nanoparticles

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of catalytic amounts of Cu-Fe nanoparticles. The process represents many advantages because it does not require additional bases or reductants, and thi

An efficient ultrasound-assisted method for the synthesis of 1,4-Disubstituted triazoles

An efficient method for the synthesis of 1,4-disubstituted triazoles has been developed with the help of ultrasound irradiation in water at room temperature. Under the optimized conditions, a novel series of 1,4-disubstituted 1,2,3-triazoles was synthesiz

Heterogeneous catalytic reactions "on Water" by using stable polymeric alkynylcopper(I) pre-catalysts: Alkyne/azide cycloaddition reactions

Dinuclear alkynylcopper(I) complexes have been found to be the active pre-catalysts in copper-catalysed cycloaddition of azides and terminal alkynes (CuAAC). These copper(I) ladderane polymers are used in "on water" CuAAC reactions, with loadings as low a

The use of glucose as alternative reducing agent in copper-catalyzed alkyne-azide cycloaddition

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of glucose and catalytic amounts of Fehling reagent. This process is carried out under ambient pressure and temperature with good yields.

Experimental evidence for the involvement of dinuclear alkynylcopper(I) complexes in alkyne-azide chemistry

Dinuclear alkynylcopper(I) ladderane complexes are prepared by a robust and simple protocol involving the reduction of Cu2(OH)3OAc or Cu-(OAc)2 by easily oxidised alcohols in the presence of terminal alkynes; they function

Alkynylcopper(i) polymers and their use in a mechanistic study of alkyne-azide click reactions

Polymeric dinuclear alkynylcopper(i) complexes, for example phenylethynylcopper(i), can be prepared by a robust method involving the interaction of terminal alkynes with copper(ii) salts in acetonitrile. The use of the ladder polymers provides heterogeneous catalysts for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions and provides important mechanistic information.