1227248-35-2Relevant academic research and scientific papers
Enantioselective synthesis of (+)- l -733,060 and (+)-CP-99,994: Application of an ireland-claisen rearrangement/michael addition domino sequence
Garrido, Narciso M.,García, Mercedes,Sánchez, M. Rosa,Díez, David,Urones, Julio G.
, p. 387 - 390 (2010)
An efficient asymmetric synthesis of (+)-l-733,060, (-)-(2S,3R)-1 and (+)-CP-99,994, starting from a Baylis-Hillman adduct, is described. The key steps include a novel domino reaction: stereoselective Ireland-Claisen rearrangement, asymmetric Michael addi
