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1-Benzyl-8-mercapto-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione is a complex organic compound belonging to the purine family, characterized by a unique molecular structure. 1-benzyl-8-mercapto-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione features a benzyl group attached to the 1-position, a thiol (mercapto) group at the 8-position, and methyl groups at the 3 and 7 positions. The molecule also contains two carbonyl groups at the 2 and 6 positions, which are part of a 3H,7H-dione system. This specific arrangement of functional groups and atoms gives the compound its distinct chemical properties and potential applications in various fields, such as pharmaceuticals or chemical research.

1228-89-3

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1228-89-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1228-89-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,2 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1228-89:
(6*1)+(5*2)+(4*2)+(3*8)+(2*8)+(1*9)=73
73 % 10 = 3
So 1228-89-3 is a valid CAS Registry Number.

1228-89-3Downstream Products

1228-89-3Relevant academic research and scientific papers

MLKL INHIBITORS

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Paragraph 0559-0560, (2018/09/26)

Purine derivatives that inhibit cellular necroptosis and/or human MLKL, pharmaceutical compositions thereof, and methods of treating an MLKL-mediated disorder with an effective amount of the compound or composition. Said MLKL-mediated disorder is pathology associated necroptosis, including ischemia-reperfusion damage, neurodegeneration, and inflammatory diseases such as acute pancreatitis, multiple sclerosis, inflammatory bowel disease, and allergic colitis.

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