1228186-19-3Relevant academic research and scientific papers
3-/3,5-Pyrrole-substituted BODIPY derivatives and their photophysical and electrochemical studies
Kadassery, Karthika J,Nimesh, Akanksha,Raj, Sanoj,Agarwal, Neeraj
, p. 1435 - 1443 (2016)
Nucleophilic substitution on 3-bromo/3,5-dibromo-4,4′-difluoro-8-(aryl)-4-bora-3a,4a-diaza-s-indacene (BODIPY), substituted with anisyl or thienyl at meso positions, with neat pyrrole afforded the mono and di-pyrrole substituted BODIPYs 1–4 in good yields
Synthesis and photophysical studies of heteroaryl substituted-BODIPy derivatives for biological applications
Lakhe, Dipti,Jairaj, Karthika K.,Pradhan, Madhura,Ladiwala, Uma,Agarwal, Neeraj
, p. 7124 - 7129 (2014)
Mono and di-heteroaryl-4,4′-difluoro-8-(aryl)-4-bora-3a,4a-diaza-s-indacene (BODIPy) (1-5) were synthesized using Suzuki-Miyaura couplings. Hetero aryl substitution on 3- or 3,5-positions caused large bathochromic shifts (up to ～150 nm) in absorption (569
Photostable BODIPY-based molecule with simultaneous type i and type II photosensitization for selective photodynamic cancer therapy
Lai, Yen-Chih,Chang, Cheng-Chung
, p. 1576 - 1583 (2014/03/21)
We introduce a new class of photostable, efficient photosensitizers based on boron-dipyrromethene (BODIPY) derivatives that can generate singlet oxygen and superoxide simultaneously under irradiation. First, we report the synthesis and design of how to control the generation of a specifically substituted position of BODIPY. Second, after biologically evaluating the uptake, localization and phototoxicity in cell lines, we conclude that 2,6-di-anisole substituted BODIPY is a potentially selective photodynamic therapy candidate because its photodamage is more efficient in cancer cells than in normal cells without significant dark toxicity.
Synthesis and photophysical properties of 3,5-bis(oxopyridinyl)- and 3,5-bis(pyridinyloxy)-substituted boron-dipyrromethenes
Khan, Tamanna K.,Rao, M. Rajeswara,Ravikanth
experimental part, p. 2314 - 2323 (2010/07/10)
Nucleophilic substitution reactions of 2-, 3- and 4-hydroxypyridines with 3,5-dibromo meso-aryl and meso-furyl borondipyrromethenes (BODIPYs) resulted in the formation of the corresponding 3,5-bis(oxopyridinyl)-BODIPYs and 3,5-bis(pyridinyloxy)-BODIPYs in decent yields. The effect of a pyridone versus an oxypyridine at the 3- and 5-positions on the spectral, electrochemical and photophysical properties were studied as a function of solvent. The 3, 5-bis(oxopyridinyl)-BODIPYs exhibit: broad, red-shifted absorption and emission bands, decreased quantum yields and lifetimes, displayed large Stokes shifts and easier reductions than did the 3, 5-bis(pyridinyloxy)-BODIPYs. The differences in the properties of these two classes of BODIPY dyes are attributed to the extension of π-delocalization associated with the electron-deficient nature of the pyridone groups.
