1228186-20-6

Upstream product

• 1228186-19-3 2,10-dibromo-meso-(4-methoxyphenyl)dipyrromethane 
• 128-08-5 N-Bromosuccinimide 
• 109-63-7 boron trifluoride diethyl etherate 
• 176446-62-1 5-(4-methoxyphenyl)dipyrromethane 
• 123-11-5 4-methoxy-benzaldehyde 
• 109-97-7 pyrrole 

Downstream Products

• 1228186-24-0 4,4-difluoro-8-(4-methoxyphenyl)-3,5-bis(pyridin-3-yloxy)-4-bora-3a,4a-diaza-s-indacene 
• 1228186-23-9 3,5-bis(1,2-dihydro-2-oxopyridin-1-yl)-4,4-difluoro-8-(4-methoxyphenyl)-4-bora-3a,4a-diaza-s-indacene 
• 1228186-25-1 3,5-bis(1,4-dihydro-4-oxopyridin-1-yl)-4,4-difluoro-8-(4-methoxyphenyl)-4-bora-3a,4a-diaza-s-indacene 
• 1567408-62-1 C₃₀H₂₅BF₂N₂O₃ 

Relevant academic research and scientific papers

Development of a Ratiometric Fluorescent Probe with Two Reactive Sulfoxides for Monitoring the Activity of Methionine Sulfoxide Reductase A

Biological oxidation of methionine side chains in proteins is a process that affects the functions of many proteins. One of the key regulators of this signaling is the enzyme methionine sulfoxide reductase A (MsrA). MsrA is implicated in a number of disea

Red-emitting fluorogenic BODIPY-tetrazine probes for biological imaging

A series of new BODIPY-tetrazine derivatives have been developed with a twist intramolecular charge transfer (TICT) state in polar solvents, which is an electron transfer process that occurs upon photoexcitation in a molecule that usually consists of an electron donor and acceptor linked by a single bond. Among them, the BODIPY-tetrazine derivative6iwas stable towards long-term storage and red-emitting with excellent performance, and was further used to imagetrans-cyclooctene-labeled lipids in mammalian cells and cyclopropene-labeled sugars in cancer cells under no-wash conditions.

3-/3,5-Pyrrole-substituted BODIPY derivatives and their photophysical and electrochemical studies

Nucleophilic substitution on 3-bromo/3,5-dibromo-4,4′-difluoro-8-(aryl)-4-bora-3a,4a-diaza-s-indacene (BODIPY), substituted with anisyl or thienyl at meso positions, with neat pyrrole afforded the mono and di-pyrrole substituted BODIPYs 1–4 in good yields

Photostable BODIPY-based molecule with simultaneous type i and type II photosensitization for selective photodynamic cancer therapy

We introduce a new class of photostable, efficient photosensitizers based on boron-dipyrromethene (BODIPY) derivatives that can generate singlet oxygen and superoxide simultaneously under irradiation. First, we report the synthesis and design of how to control the generation of a specifically substituted position of BODIPY. Second, after biologically evaluating the uptake, localization and phototoxicity in cell lines, we conclude that 2,6-di-anisole substituted BODIPY is a potentially selective photodynamic therapy candidate because its photodamage is more efficient in cancer cells than in normal cells without significant dark toxicity.

Synthesis and photophysical studies of heteroaryl substituted-BODIPy derivatives for biological applications

Mono and di-heteroaryl-4,4′-difluoro-8-(aryl)-4-bora-3a,4a-diaza-s-indacene (BODIPy) (1-5) were synthesized using Suzuki-Miyaura couplings. Hetero aryl substitution on 3- or 3,5-positions caused large bathochromic shifts (up to ～150 nm) in absorption (569

Brominated boron dipyrrins: Synthesis, structure, spectral and electrochemical properties

meso-Anisyl boron dipyrrins (BODIPYs) 1-6 containing one to six bromines at the pyrrole carbons have been synthesized by treating meso-anisyl dipyrromethane with 'n' equivalents of N-bromosuccinimide in THF at room temperature followed by oxidation with D

Synthesis and photophysical properties of 3,5-bis(oxopyridinyl)- and 3,5-bis(pyridinyloxy)-substituted boron-dipyrromethenes

Nucleophilic substitution reactions of 2-, 3- and 4-hydroxypyridines with 3,5-dibromo meso-aryl and meso-furyl borondipyrromethenes (BODIPYs) resulted in the formation of the corresponding 3,5-bis(oxopyridinyl)-BODIPYs and 3,5-bis(pyridinyloxy)-BODIPYs in decent yields. The effect of a pyridone versus an oxypyridine at the 3- and 5-positions on the spectral, electrochemical and photophysical properties were studied as a function of solvent. The 3, 5-bis(oxopyridinyl)-BODIPYs exhibit: broad, red-shifted absorption and emission bands, decreased quantum yields and lifetimes, displayed large Stokes shifts and easier reductions than did the 3, 5-bis(pyridinyloxy)-BODIPYs. The differences in the properties of these two classes of BODIPY dyes are attributed to the extension of π-delocalization associated with the electron-deficient nature of the pyridone groups.