122856-01-3 Usage
Chemical Properties
Colourless Liquid
Uses
N-succinimidyl 3-(trimethylstannyl)benzoate is a compound used potentially for the radioiodination of monoclonal antibodies. Used in Antibody labelling.
Check Digit Verification of cas no
The CAS Registry Mumber 122856-01-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,8,5 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 122856-01:
(8*1)+(7*2)+(6*2)+(5*8)+(4*5)+(3*6)+(2*0)+(1*1)=113
113 % 10 = 3
So 122856-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H8NO4.3CH3.Sn/c13-9-6-7-10(14)12(9)16-11(15)8-4-2-1-3-5-8;;;;/h1-2,4-5H,6-7H2;3*1H3;/rC14H17NO4Sn/c1-20(2,3)11-6-4-5-10(9-11)14(18)19-15-12(16)7-8-13(15)17/h4-6,9H,7-8H2,1-3H3
122856-01-3Relevant articles and documents
RADIOIODINATION METHOD
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Page/Page column 27, (2010/08/09)
The present invention provides a method for the synthesis of radioiodinated compounds which is advantageous over prior art methods. Using a hydrazine or an aminoxy in place of a primary amine for indirect radioiodination facilitates a much quicker reaction thus reducing reaction time and increasing the yield. In addition, where there are primary amines in the molecule to be radioiodinated, such as the N-terminus of a peptide or lysine residues, reaction at the hydrazine or aminoxy is greatly favoured.
