122856-01-3 Usage
Uses
Used in Antibody Labelling:
N-succinimidyl 3-(trimethylstannyl)benzoate is used as a reagent for the radioiodination of monoclonal antibodies. This process allows for the attachment of radioactive iodine to antibodies, which can then be used for diagnostic or therapeutic purposes.
Used in Medical Research and Diagnostics:
In the medical research and diagnostics industry, N-succinimidyl 3-(trimethylstannyl)benzoate is used as a reagent for antibody labelling. This enables the tracking and detection of specific biological targets, such as proteins or cells, which is crucial for understanding disease mechanisms and developing targeted therapies.
Used in Pharmaceutical Development:
N-succinimidyl 3-(trimethylstannyl)benzoate is also utilized in the pharmaceutical industry for the development of drugs that target specific biological pathways. By using N-succinimidyl 3-(trimethylstannyl)benzoate for antibody labelling, researchers can gain insights into the mechanisms of action of potential therapeutic agents and optimize their efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 122856-01-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,8,5 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 122856-01:
(8*1)+(7*2)+(6*2)+(5*8)+(4*5)+(3*6)+(2*0)+(1*1)=113
113 % 10 = 3
So 122856-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H8NO4.3CH3.Sn/c13-9-6-7-10(14)12(9)16-11(15)8-4-2-1-3-5-8;;;;/h1-2,4-5H,6-7H2;3*1H3;/rC14H17NO4Sn/c1-20(2,3)11-6-4-5-10(9-11)14(18)19-15-12(16)7-8-13(15)17/h4-6,9H,7-8H2,1-3H3
122856-01-3Relevant academic research and scientific papers
RADIOIODINATION METHOD
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Page/Page column 27, (2010/08/09)
The present invention provides a method for the synthesis of radioiodinated compounds which is advantageous over prior art methods. Using a hydrazine or an aminoxy in place of a primary amine for indirect radioiodination facilitates a much quicker reaction thus reducing reaction time and increasing the yield. In addition, where there are primary amines in the molecule to be radioiodinated, such as the N-terminus of a peptide or lysine residues, reaction at the hydrazine or aminoxy is greatly favoured.
