161767-56-2

Usage

Uses

Used in Organic Synthesis:
3-Trimethylstannyl Benzoic Acid is used as a synthetic building block for the development of a wide range of organic compounds. Its application in organic synthesis is due to its ability to facilitate the formation of new chemical bonds and contribute to the creation of complex molecular structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Trimethylstannyl Benzoic Acid is used as a key intermediate in the synthesis of various drugs and drug candidates. Its role in this industry is to provide a stable and reliable starting material for the development of new medications with potential therapeutic benefits.
Used in Chemical Research:
3-Trimethylstannyl Benzoic Acid is also employed in chemical research as a valuable tool for studying the properties and reactivity of organotin compounds. Its use in research helps scientists gain a deeper understanding of the underlying chemical processes and mechanisms involved in various reactions, ultimately contributing to the advancement of chemical knowledge and innovation.
Used in Material Science:
In the field of material science, 3-Trimethylstannyl Benzoic Acid is utilized as a component in the development of novel materials with specific properties. Its application in this industry is driven by its potential to contribute to the creation of materials with enhanced performance characteristics, such as improved stability, reactivity, or functionality.

Upstream product

• 661-69-8 hexamethyldistannane 
• 618-51-9 3-Iodobenzoic acid 
• 179942-37-1 methyl 3-(trimethylstannyl)benzoate 
• 146920-17-4 1-(3-carboxyphenyl)-3,3-diisopropyltriazene 
• 99-05-8 meta-aminobenzoic acid 

Downstream Products

• 122856-01-3 N-succinimidyl meta-trimethylstannylbenzoate 

Relevant academic research and scientific papers

Synthesis of Aryl Trimethylstannane via BF3·OEt2-Mediated Cross-Coupling of Hexaalkyl Distannane Reagent with Aryl Triazene at Room Temperature

BF3·OEt2-mediated cross-coupling of (SnMe3)2 with aryl triazene offers a new strategy for the synthesis of aryl stannane. A variety of synthetically useful aryl trimethylstannanes were produced in moderate to good yields with this metal-free approach. One-pot sequential Stille cross-coupling with different aryl bromides provides a short entry to both symmetrical and unsymmetrical biaryl compounds.

Synthesis of aryl trimethylstannanes from aryl halides: An efficient photochemical method

An efficient transition-metal-free photochemical method featuring excellent functional group tolerance, mild reaction conditions and short reaction times has been discovered and developed for the synthesis of (hetero)aryl trimethylstannanes from (hetero)aryl halides. A photo-initiated radical chain mechanism was proposed based on preliminary mechanistic studies.

RADIOIODINATION METHOD

The present invention provides a method for the synthesis of radioiodinated compounds which is advantageous over prior art methods. Using a hydrazine or an aminoxy in place of a primary amine for indirect radioiodination facilitates a much quicker reaction thus reducing reaction time and increasing the yield. In addition, where there are primary amines in the molecule to be radioiodinated, such as the N-terminus of a peptide or lysine residues, reaction at the hydrazine or aminoxy is greatly favoured.

Synthesis of 5- and 6-Substituted 2-Methylbenzothiazoles under Conditions of Metal Complex Catalysis

Methods are proposed for preparation of 5- and 6-substituted 2-methylbenzothiazoles by reactions of organozinc and organotin compounds with 5- and 6-bromo-2-methylbenzothiazoles, catalyzed by palladium complexes. The reactions of organozinc compounds with 5(6)-bromo-2-methylbenzothiazoles occur in THF at 20°C in the presence of PdCl2(dppf), and those of organotin compounds are carried out in DMF, aqueous DMF, or water at 40-100°C in the presence of PdCl2, Pd(OAc)2, or PdCl2(PPh3)2.