122860-79-1

Upstream product

• 122-78-1 phenylacetaldehyde 
• 74-89-5 methylamine 
• 593-51-1 methylamine hydrochloride 

Downstream Products

• 1329672-35-6 3-(benzyl)-2-methyl-1,2-thiazetidine-1,1-dioxide 
• 183555-52-4 2-chloro-N-methyl-N-(2-(E)-phenylethenyl)acetamide 
• 144175-35-9 N-(1-diphenyloxophosphinyl-1-benzyl)methyl-N-methyl benzamide 
• 86770-02-7 3-Benzyl-2,3-dihydro-2-methyl-1H-isoindol-1-one 
• 19883-34-2 (E)-N-Methyl-N-(2-phenylethenyl)benzamide 
• 77130-13-3 N-Methylthiophenylacetamide 
• 141738-98-9 N-Methyl-2-phenyl-thioacetimidic acid methyl ester; hydriodide 

Relevant academic research and scientific papers

3-Thiolated 2-azetidinones: Synthesis and in vitro antibacterial and antifungal activities

A series of 3-thiolated β-lactams were synthesized by [2+2] ketene-imine cycloaddition reaction from S-substituted mercaptoacetic acids and Schiff bases. Then, some of the 3-methylthio β-lactams were converted to 3-(methylsulfinyl) β-lactams and 3-(methylsulfonyl) β-lactams using m-CPBA under different reaction conditions. All the compounds were characterized by spectral data and elemental analyses and were evaluated for their in vitro antibacterial and antifungal activities against pathogenic strains including Staphylococcus aureus (Methicillin resistant strain). The preliminary screening results indicated that some of these compounds demonstrated moderate to very good antibacterial and antifungal activities.

An elegant synthesis of Zetaclausenamide

Zetaclausenamide, which was isolated as a hepatoprotective agent from the leaves of medicinal plant Clausena lansium, was synthesized for the first time in six steps including Darzen's condensation, photoisomerization, and the final cyclization reactions.

Regiochemistry in aryl radical cyclisations (5-exo versus 6-endo) of N-vinylic 2-iodobenzamides

Bu3SnH-mediated aryl radical cyclisations of a range of N-vinylic 2-iodobenzamides 10 were examined. The enamides 10a-d gave exclusively the 5-exo cyclisation products 11a-d, whereas the enamides 10e,f having a phenyl substituent on the vinylic carbon ato

A simple, convenient and general method for the synthesis of N-acylalkylaminomethyl- and N-acylalkylamino(alkyl, aryl, heteroaryl)methylphosphonates and -phosphine oxides

A variety of N-acylalkylaminomethyl- and alkylamino(alkyl, aryl, heteroaryl)methylphosphonates and -phosphine oxides has been efficiently prepared by acylation of suitable Schiff bases and subsequent treatment of the chloromethylcarboxamide intermediates with the appropriate phosphorylating agent.

Dicoordinated Phosphorus Compounds: a Novel 4,5-Disubstituted 1,2,3,4-Triazaphosphole. X-Ray Molecular Structures of a 2-N-BF3 Complex of 4,5-Diisopropyl-1,2,3,4-triazaphosphole and of its Tetramer. Conformation in the Crystalline Form and in Solution

The synthesis of the title compound is described.It may be stabilised by the reaction of its tetramer with BF3.The tetramer displays several isomers and conformers in solution; one of them has been isolated and its crystal structure determined.The crystal structure of the 2-N-BF3 complex of the parent 4,5-diisopropyl-1,2,3,4-triazaphosphole has also been obtained.