1229245-19-5

Basic information

• Product Name: 3-bromo-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzoic acid
• Synonyms: 3-bromo-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzoic acid
• CAS NO: 1229245-19-5
• Molecular Weight: 283.122
• Mol File: 1229245-19-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-bromo-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzoic acid(1229245-19-5)
• EPA Substance Registry System: 3-bromo-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzoic acid(1229245-19-5)

Safety Data

• Hazardous Substances Data: 1229245-19-5(Hazardous Substances Data)

Upstream product

• 7697-26-9 3-bromo-4-methylbenzoic acid 
• 1229245-20-8 3-bromo-5-iodo-4-methylbenzoic acid 
• 627-41-8 propargyl alcohol methyl ether 

Downstream Products

• 1229245-18-4 3-bromo-N-cyclopropyl-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzamide 
• 1312350-29-0 (3R,4S)-N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]-N-cyclopropyl-4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)-piperidine-3-carboxamide 
• 1194488-55-5 N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]cyclopropanamine 
• 1312350-26-7 tert-butyl (3R,4S)-3-{[[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl](cyclopropyl)amino]carbonyl}-4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)piperidine-1-carboxylate 
• 1229245-21-9 3-bromo-N-cyclopropyl-5-(3-methoxypropyl)-4-methylbenzamide 
• 1194491-85-4 N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]cyclopropanamine mesylate 
• 1312350-32-5 (3R,4S)-N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]-N-cyclopropyl-4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)-piperidine-3-carboxamide hydrochloride 
• 1194488-76-0 3-{3-bromo-5-[(cyclopropylamino)methyl]-2-methylphenyl}-1-propanol 

Relevant articles and documents

Convergent kilo-scale synthesis of a potent renin inhibitor for the treatment of hypertension

Process research and development of a synthetic route towards a novel renin inhibitor (1) is described. The highly convergent synthetic route provided 1 in 15% yield on multikilogram scale with a longest linear sequence of 11 steps. The use of catalytic h