1229403-09-1Relevant articles and documents
Amphipathic α-helix mimetics based on a 1,2-diphenylacetylene scaffold
Jung, Kwan-Young,Vanommeslaeghe, Kenno,Lanning, Maryanna E.,Yap, Jeremy L.,Gordon, Caryn,Wilder, Paul T.,Mackerell, Alexander D.,Fletcher, Steven
, p. 3234 - 3237 (2013)
In order to mimic amphipathic α-helices, a novel scaffold based on a 1,2-diphenylacetylene was designed. NMR and computational modeling confirmed that an intramolecular hydrogen bond favors conformations of the 1,2-diphenylacetylene that allow for accurat
Cyclopropylmethyl Protection of Phenols: Total Synthesis of the Resveratrol Dimers Anigopreissin A and Resveratrol–Piceatannol Hybrid
Kumar, Arvind,Saleeb, Michael,Werz, Dominik,Elofsson, Mikael
, p. 953 - 956 (2018/11/23)
We demonstrate the versatile use of the cyclopropylmethyl group to protect phenols through the total synthesis of two benzofuran-based natural products, that is, anigopreissin A and the resveratrol–piceatannol hybrid. This protecting group is a good alter